Serotonin transporter occupancy induced by paroxetine in patients with major depression disorder: a 123I-ADAM SPECT study

被引:0
|
作者
Ana M. Catafau
Victor Perez
Pedro Plaza
Juan-Carlos Pascual
Santiago Bullich
Marina Suarez
Maria M. Penengo
Iluminada Corripio
Dolors Puigdemont
Monica Danus
Javier Perich
Enric Alvarez
机构
[1] Psychiatry Centre of Excellence for Drug Discovery,Experimental Medicine, Clinical Pharmacology Discovery Medicine
[2] GlaxoSmithKline,Centre for Imaging in Psychiatry, CRC
[3] Hospital del Mar,Mar
[4] Hospital Sant Pau,Psychiatry Department
[5] Hospital del Mar,Magnetic Resonance Department, CRC
来源
Psychopharmacology | 2006年 / 189卷
关键词
I-ADAM SPECT; Serotonin transporter; Serotonin transporter availability; Major depression disorder; Paroxetine; Occupancy; Pharmacology;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:145 / 153
页数:8
相关论文
共 50 条
  • [41] Association between somatization subscale score and serotonin transporter availability in healthy volunteers-a single photon emission computed tomography study with [123I] ADAM
    Chou, Ming Hui
    Chen, Kao Chin
    Yeh, Tzung Lieh
    Lee, I. Hui
    Yao, Wei Jen
    Chen, Po See
    Chang, Kang-Wei
    Liao, Mei-Hsiu
    Yang, Yen Kuang
    PSYCHOPHARMACOLOGY, 2012, 219 (04) : 1011 - 1016
  • [42] Suicidal ideation modulates the reduction in serotonin transporter availability in male military conscripts with major depression: A 4-[18F]-ADAM PET study
    Yeh, Yi-Wei
    Ho, Pei-Shen
    Chen, Chun-Yen
    Kuo, Shin-Chang
    Liang, Chih-Sung
    Yen, Che-Hung
    Huang, Chang-Chih
    Shiue, Chyng-Yann
    Huang, Wen-Sheng
    Ma, Kuo-Hsing
    Lu, Ru-Band
    Huang, San-Yuan
    WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2015, 16 (07) : 502 - 512
  • [43] Distribution volume ratio of serotonin and dopamine transporters in euthymic patients with a history of major depression - a dual-isotope SPECT study
    Hsieh, Pei Chun
    Lee, I. Hui
    Yeh, Tzung Lieh
    Chen, Kao Chin
    Huang, Hui Chun
    Chen, Po See
    Yang, Yen Kuang
    Yao, Wei Jen
    Lu, Ru-Band
    Chiu, Nan Tsing
    PSYCHIATRY RESEARCH-NEUROIMAGING, 2010, 184 (03) : 157 - 161
  • [44] Quantification of striatal dopamine transporters with 123I-FP-CIT SPECT is influenced by the selective serotonin Reuptake inhibitor paroxetine:: A double-blind, placebo-controlled, crossover study in healthy control subjects
    Booij, Jan
    de Jong, Jan
    de Bruin, Kora
    Knol, Remco
    de Win, Maartje M. L.
    van Eck-Smit, Berthe L. F.
    JOURNAL OF NUCLEAR MEDICINE, 2007, 48 (03) : 359 - 366
  • [45] Lower availability of midbrain serotonin transporter between healthy subjects with and without a family history of major depressive disorder - a preliminary two-ligand SPECT study
    Hsieh, P. C.
    Chen, K. C.
    Yeh, T. L.
    Lee, I. H.
    Chen, P. S.
    Yao, W. J.
    Chiu, N. -T.
    Chen, C. -C.
    Liao, M. -H.
    Yang, Y. K.
    EUROPEAN PSYCHIATRY, 2014, 29 (07) : 414 - 418
  • [46] Serotonin Modulates the Correlations between Obsessive-compulsive Trait and Heart Rate Variability in Normal Healthy Subjects: A SPECT Study with [123I]ADAM and Heart Rate Variability Measurement
    Kuo, Che Yu
    Chen, Kao Chin
    Lee, I. Hui
    Tseng, Huai-Hsuan
    Chiu, Nan Tsing
    Chen, Po See
    Yang, Yen Kuang
    Chang, Wei Hung
    CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, 2022, 20 (02) : 271 - 278
  • [47] Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study
    M Reimold
    A Batra
    A Knobel
    M N Smolka
    A Zimmer
    K Mann
    C Solbach
    G Reischl
    F Schwärzler
    G Gründer
    H-J Machulla
    R Bares
    A Heinz
    Molecular Psychiatry, 2008, 13 : 606 - 613
  • [48] Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography
    Malison, RT
    Price, LH
    Berman, R
    van Dyck, CH
    Pelton, GH
    Carpenter, L
    Sanacora, G
    Owens, MJ
    Nemeroff, CB
    Rajeevan, N
    Baldwin, RM
    Seibyl, JP
    Innis, RB
    Charney, DS
    BIOLOGICAL PSYCHIATRY, 1998, 44 (11) : 1090 - 1098
  • [49] Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression:: a [11C]DASB PET study
    Reimold, M.
    Batra, A.
    Knobel, A.
    Smolka, M. N.
    Zimmer, A.
    Mann, K.
    Solbach, C.
    Reischl, G.
    Schwaerzler, F.
    Gruender, G.
    Machulla, H-J
    Bares, R.
    Heinz, A.
    MOLECULAR PSYCHIATRY, 2008, 13 (06) : 606 - 613
  • [50] Loss of thalamic serotonin transporters in early drug-naive Parkinson's disease patients is associated with tremor:: an [123I]β-CIT SPECT study
    Caretti, V.
    Stoffers, D.
    Winogrodzka, A.
    Isaias, I. -U.
    Costantino, G.
    Pezzoli, G.
    Ferrarese, C.
    Antonini, A.
    Wolters, E. -Ch.
    Booij, J.
    JOURNAL OF NEURAL TRANSMISSION, 2008, 115 (05) : 721 - 729