Serotonin transporter occupancy induced by paroxetine in patients with major depression disorder: a 123I-ADAM SPECT study

被引:0
|
作者
Ana M. Catafau
Victor Perez
Pedro Plaza
Juan-Carlos Pascual
Santiago Bullich
Marina Suarez
Maria M. Penengo
Iluminada Corripio
Dolors Puigdemont
Monica Danus
Javier Perich
Enric Alvarez
机构
[1] Psychiatry Centre of Excellence for Drug Discovery,Experimental Medicine, Clinical Pharmacology Discovery Medicine
[2] GlaxoSmithKline,Centre for Imaging in Psychiatry, CRC
[3] Hospital del Mar,Mar
[4] Hospital Sant Pau,Psychiatry Department
[5] Hospital del Mar,Magnetic Resonance Department, CRC
来源
Psychopharmacology | 2006年 / 189卷
关键词
I-ADAM SPECT; Serotonin transporter; Serotonin transporter availability; Major depression disorder; Paroxetine; Occupancy; Pharmacology;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:145 / 153
页数:8
相关论文
共 50 条
  • [21] Brain and platelet serotonin transporter in humans -: correlation between [123I]-ADAM SPECT and serotonergic measurements in platelets
    Uebelback, Ralf
    Franke, Leonora
    Herold, Nathalie
    Plotkin, Michael
    Amthauer, Holger
    Felix, Roland
    NEUROSCIENCE LETTERS, 2006, 406 (03) : 153 - 158
  • [22] Brain SPECT imaging and whole-body biodistribution with [123I]ADAM -: a serotonin transporter radiotracer in healthy human subjects
    Lin, KJ
    Liu, CY
    Wey, SP
    Hsiao, IT
    Wu, J
    Fu, YK
    Yen, TC
    NUCLEAR MEDICINE AND BIOLOGY, 2006, 33 (02) : 193 - 202
  • [23] SPECT of serotonin transporters using 123I-ADAM:: Optimal imaging time after bolus injection and long-term test-retest in healthy volunteers
    Catafau, AM
    Pérez, V
    Penengo, MM
    Bullich, S
    Danús, M
    Puigdemont, D
    Pascual, JC
    Corripio, I
    Llop, J
    Perich, J
    Alvarez, E
    JOURNAL OF NUCLEAR MEDICINE, 2005, 46 (08) : 1301 - 1309
  • [24] Association of thalamic serotonin transporter and interleukin-10 in bipolar I disorder: a SPECT study
    Hsu, Ju-Wei
    Lirng, Jiing-Feng
    Wang, Shyh-Jen
    Lin, Chun-Lung
    Yang, Kai-Chun
    Liao, Mei-Hsiu
    Chou, Yuan-Hwa
    BIPOLAR DISORDERS, 2014, 16 (03) : 241 - 248
  • [25] Dopamine and serotonin transporter availability in chronic heroin users: A [123I]β-CIT SPECT imaging study
    Cosgrove, Kelly P.
    Tellez-Jacques, Karen
    Pittman, Brian
    Petrakis, Ismene
    Baldwin, Ronald M.
    Tamagnan, Gilles
    Seibyl, John
    Kosten, Thomas
    Staley, Julie K.
    PSYCHIATRY RESEARCH-NEUROIMAGING, 2010, 184 (03) : 192 - 195
  • [26] [123I]β-CIT SPECT demonstrates decreased brain dopamine and serotonin transporter levels in untreated parkinsonian patients
    Haapaniemi, TH
    Ahonen, A
    Torniainen, P
    Sotaniemi, KA
    Myllylä, VV
    MOVEMENT DISORDERS, 2001, 16 (01) : 124 - 130
  • [27] [123I]-β-CIT SPECT imaging shows reduced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder
    Willeit, M
    Praschak-Rieder, N
    Neumeister, A
    Pirker, W
    Asenbaum, S
    Vitouch, O
    Tauscher, J
    Hilger, E
    Stastny, J
    Brücke, T
    Kasper, S
    BIOLOGICAL PSYCHIATRY, 2000, 47 (06) : 482 - 489
  • [29] Decreased brain serotonin transporter binding in the euthymic state of bipolar I but not bipolar II disorder: a SPECT study
    Chou, Yuan-Hwa
    Wang, Shyh-Jen
    Lin, Chun-Lung
    Mao, Wei-Chung
    Lee, Shin-Min
    Liao, Mei-Hsiu
    BIPOLAR DISORDERS, 2010, 12 (03) : 312 - 318
  • [30] Midbrain serotonin transporters in de novo and L-DOPA-treated patients with early Parkinson's disease - a [123I]-ADAM SPECT study
    Beucke, J. C.
    Plotkin, M.
    Winter, C.
    Endrass, T.
    Amthauer, H.
    Juckel, G.
    Kupsch, A.
    EUROPEAN JOURNAL OF NEUROLOGY, 2011, 18 (05) : 750 - 755