Olfactory ensheathing cell transplantation as a strategy for spinal cord repair—what can it achieve?

被引:0
作者
Susan C Barnett
John S Riddell
机构
[1] University of Glasgow,SC Barnett is Professor of Cellular Neuroscience in the Division of Clinical Neuroscience, and JS Riddell is a Senior Lecturer in the Division of Neuroscience and Biomedical Systems at the Institute of Biomedical and Life Sciences
[2] Glasgow,undefined
[3] UK.,undefined
来源
Nature Clinical Practice Neurology | 2007年 / 3卷
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摘要
Numerous lines of evidence from animal studies indicate that transplants of olfactory ensheathing cells—glial cells derived from the olfactory system—can promote functional recovery in the injured spinal cord. In this Review, Barnett and Riddell analyze this evidence and examine the mechanisms by which repair might be achieved, as well as assessing the prospects for translating this approach into the clinic.
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页码:152 / 161
页数:9
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[11]  
Dumont RJ(2004)Olfactory ensheathing cells: going solo or in need of a friend? Trends Neurosci 27 54-60
[12]  
Reier P(2002)Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair Brain Res Bul 57 833-888
[13]  
Norenberg MD(2001)Olfactory ensheathing cells—another miracle cure for spinal cord injury? Nat Rev Neurosci 2 369-375
[14]  
Barnett SC(2002)Olfactory ensheathing glia and Schwann cells: two of a kind? Cell Tissue Res 309 337-345
[15]  
Chang L(1990)Olfactory neurogenesis: genetic or environmental controls? Trends Neurosci 13 362-365
[16]  
Blesch A(2002)Neural regeneration and the peripheral olfactory system Anat Rec 269 33-49
[17]  
Raisman G(1973)Cell dynamics in the olfactory mucosa Tissue Cell 5 113-131
[18]  
Wewetzer K(1990)Glial influences on axonal growth in the primary olfactory system Glia 3 433-449
[19]  
Farbman AI(1985)Specialized neuroglial arrangement may explain the capacity of vomeronasal axons to reininervate central neurons Neuroscience 14 237-254
[20]  
Schwob JE(1993)Purification of olfactory nerve ensheathing cells from the olfactory bulb Dev Biol 155 337-350