Clinical and Translational Potential of MRI Evaluation in Knee Osteoarthritis

被引:0
作者
Daichi Hayashi
Ali Guermazi
C. Kent Kwoh
机构
[1] Boston University School of Medicine,Quantitative Imaging Center, Department of Radiology
[2] Yale University School of Medicine,Department of Radiology, Bridgeport Hospital
[3] University of Arizona Arthritis Center,Division of Rheumatology
来源
Current Rheumatology Reports | 2014年 / 16卷
关键词
Osteoarthritis; Magnetic resonance imaging; MRI; MRI evaluation; Radiography; Cartilage; Bone marrow lesion; Synovitis; Meniscus; Meniscal root; Semiquantitative; Quantitative; Knee;
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摘要
Magnetic resonance imaging (MRI) has become an increasingly important imaging technique in osteoarthritis (OA) research, and is widely used in the ongoing endeavor to understand the pathogenesis of OA and to develop structure and disease-modifying OA drugs. MRI offers semiquantitative, quantitative and compositional evaluation of knee OA, and enables visualization of tissues that are not seen by radiography, including but not limited to cartilage, meniscus, bone marrow lesions, synovitis, and muscles. It is now recognized that contrast-enhanced MRI enables more accurate evaluation of synovitis than MRI without contrast. Because of its ability to visualize multiple pain-related tissue pathology in three dimensions, MRI is the best modality for imaging of OA.
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