Clinical and Translational Potential of MRI Evaluation in Knee Osteoarthritis

被引：0
作者：
Daichi Hayashi
Ali Guermazi
C. Kent Kwoh
机构：
[1] Boston University School of Medicine,Quantitative Imaging Center, Department of Radiology
[2] Yale University School of Medicine,Department of Radiology, Bridgeport Hospital
[3] University of Arizona Arthritis Center,Division of Rheumatology
来源：
Current Rheumatology Reports | 2014年 / 16卷
关键词：
Osteoarthritis; Magnetic resonance imaging; MRI; MRI evaluation; Radiography; Cartilage; Bone marrow lesion; Synovitis; Meniscus; Meniscal root; Semiquantitative; Quantitative; Knee;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Magnetic resonance imaging (MRI) has become an increasingly important imaging technique in osteoarthritis (OA) research, and is widely used in the ongoing endeavor to understand the pathogenesis of OA and to develop structure and disease-modifying OA drugs. MRI offers semiquantitative, quantitative and compositional evaluation of knee OA, and enables visualization of tissues that are not seen by radiography, including but not limited to cartilage, meniscus, bone marrow lesions, synovitis, and muscles. It is now recognized that contrast-enhanced MRI enables more accurate evaluation of synovitis than MRI without contrast. Because of its ability to visualize multiple pain-related tissue pathology in three dimensions, MRI is the best modality for imaging of OA.
引用
收藏
相关论文
共 205 条
  • [1] Guermazi A(2013)Inadequacy of radiographs: one cause for failure of clinical trials to identify a disease modifying drug for osteoarthritis Arthritis Rheum 345 e5339-630
  • [2] Roemer FW(2012)Prevalence of abnormalities in knees detected by MRI in adults without knee osteoarthritis: population based observational study (Framingham Osteoarthritis Study) BMJ 8 622-251
  • [3] Felson DT(2012)Recent advances in osteoarthritis imaging—the Osteoarthritis Initiative Nat Rev Rheumatol 9 236-321
  • [4] Guermazi A(2013)MRI-based semiquantitative scoring of joint pathology in osteoarthritis Nat Rev Rheumatol 19 295-e131
  • [5] Niu J(2011)Magnetic resonance imaging in knee osteoarthritis research: semiquantitative and compositional assessment Magn Reson Imaging Clin N Am 80 e126-1398
  • [6] Hayashi D(2011)Semiquantitative assessment of focal cartilage damage at 3T MRI: a comparative study of dual echo at steady state (DESS) and intermediate-weighted (IW) fat suppressed fast spin echo sequences Eur J Radiol 12 198-1002
  • [7] Eckstein F(2011)Semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts of the knee at 3T MRI: a comparison between intermediate-weighted fat-suppressed spin echo and dual echo steady state sequences BMC Musculoskelet Disord 20 1391-641
  • [8] Wirth W(2012)Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral joint—the MOST study Osteoarthritis Cartilage 19 990-313
  • [9] Nevitt MC(2011)Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI osteoarthritis knee score) Osteoarthritis Cartilage. 41 633-948
  • [10] Guermazi A(2012)Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle aged subjects—data from the Osteoarthritis Initiative Skeletal Radiol 21 306-1547
12345678910