Human umbilical cord mesenchymal stem cell-derived exosomal miR-27b attenuates subretinal fibrosis via suppressing epithelial–mesenchymal transition by targeting HOXC6

被引:0
作者
Dongli Li
Junxiu Zhang
Zijia Liu
Yuanyuan Gong
Zhi Zheng
机构
[1] Shanghai Jiao Tong University School of Medicine,Department of Ophthalmology, Shanghai General Hospital
[2] National Clinical Research Center for Eye Diseases,undefined
[3] Shanghai Key Laboratory of Ocular Fundus Diseases,undefined
[4] Shanghai Engineering Center for Visual Science and Photomedicine,undefined
来源
Stem Cell Research & Therapy | / 12卷
关键词
Epithelial–mesenchymal transition; Exosomes; Subretinal fibrosis; Mesenchymal stem cells;
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  • [1] Ishikawa K(2016)Molecular mechanisms of subretinal fibrosis in age-related macular degeneration Exp Eye Res 142 19-25
  • [2] Kannan R(2019)Galectin-1 promotes choroidal neovascularization and subretinal fibrosis mediated via epithelial-mesenchymal transition FASEB J 33 2498-2513
  • [3] Hinton DR(2016)Non-responsiveness to intravitreal aflibercept treatment in neovascular age-related macular degeneration: implications of serous pigment epithelial detachment Sci Rep 6 29619-11
  • [4] Wu D(2011)Development of subretinal fibrosis after anti-VEGF treatment in neovascular age-related macular degeneration Ophthalmic Surg Lasers Imaging 42 6-666
  • [5] Kanda A(2014)Risk of scar in the comparison of age-related macular degeneration treatments trials Ophthalmology. 121 656-461
  • [6] Liu Y(2018)Tomographic biomarkers predicting progression to fibrosis in treated Neovascular age-related macular degeneration: a multimodal imaging study Ophthalmol Retina 2 451-49
  • [7] Kase S(2020)Caveolin-1 promotes cellular senescence in exchange for blocking subretinal fibrosis in age-related macular degeneration Invest Ophthalmol Vis Sci 61 21-2037
  • [8] Noda K(2018)Mammalian MSC from selected species: features and applications Cytometry A 93 32-948
  • [9] Ishida S(2020)Progress of mesenchymal stem cell-derived exosomes in tissue repair Curr Pharm Des 26 2022-17
  • [10] Nagai N(2012)Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials Biochim Biophys Acta 1820 940-714