Volumetric study on the inclusion complex formation of α- and β-cyclodextrin with 1-alkanols at different temperatures

被引:0
作者
Masahiro Manabe
Toshihiro Ochi
Hideo Kawamura
Hajime Katsu-ura
Masaki Shiomi
Mandeep Singh Bakshi
机构
[1] Niihama National College of Technology,Department of Applied Chemistry and Biotechnology
[2] Guru Nanak Dev University,Department of Chemistry
来源
Colloid and Polymer Science | 2005年 / 283卷
关键词
Cyclodextrin; Alcohol; Inclusion complex; Partial molar volume; Binding constant; Temperature dependence; Volume;
D O I
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中图分类号
学科分类号
摘要
The partial molar volumes (Va) of 1-alkanols (carbon number, m=5, 6, 7) in α- and β-cyclodextrin (CD) solutions at 5.00 mmol kg−1 have been determined as a function of alkanol concentration (Ca) between 293.2 and 308.2 K by using a dilatometer. It has been observed that with an increase in Ca, Va increased in α-CD solution but decreased in β-CD solution, asymptotically to a value of Va in CD-free water. The dependence of Va on Ca provided the binding constant (K) of 1:1 complex, the volume change in complex formation, and the partial molar volume of complex itself. The complex formation mechanism has been discussed on the basis of these values and their carbon number dependences in the respect of geometric behavior, hydrophobic interaction, and van der Waals interaction. It is concluded that the CD cavity in water is not rigid but flexible for fitting in nicely with guest molecule.
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页码:738 / 746
页数:8
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