Effect of Dielectric Barrier Discharge Treatment of Blood Plasma to Improve Rheological Properties of Blood

被引:0
作者
Jin M. Jung
Yong Yang
Dong H. Lee
Greg Fridman
Alexander Fridman
Young I. Cho
机构
[1] Drexel University,Department of Mechanical Engineering and Mechanics
[2] Chonbuk National University,Department of Mechanical Design Engineering, Engineering College
[3] Drexel University,School of Biomedical Engineering
来源
Plasma Chemistry and Plasma Processing | 2012年 / 32卷
关键词
Dielectric barrier discharge (DBD); Blood viscosity; Filtration; Fibrinogen; LDL;
D O I
暂无
中图分类号
学科分类号
摘要
The whole blood viscosity (WBV) is one of the major independent indicators for the risk of cardiovascular disease, stroke, and peripheral arterial diseases. Furthermore, oxidized LDL molecules are known to cause atherosclerotic plaques in arteries, and it is one of the key components that increase WBV. The present study attempted to reduce WBV by coagulating plasma proteins and lipid molecules from blood plasma using non-thermal dielectric barrier discharge (DBD) and removing them through filtration. The DBD treatment was found to produce coagulated particles in blood plasma. After filtration of the coagulated particles, WBV decreased by 9.1 and 17.7% for both systolic and diastolic blood viscosities, respectively. The present results suggest that the removal of excess plasma proteins and lipid molecules might be feasible using DBD treatment.
引用
收藏
页码:165 / 176
页数:11
相关论文
共 280 条
  • [1] Lee AJ(1998)Blood viscosity and elevated carotid intima-media thickness in men and women: the Edinburgh Artery Study Circulation 97 1467-143
  • [2] Mowbray PI(2007)Acute myocardial infarction in young adults: evaluation of the haemorheological pattern at the initial stage, after 3 and 12 months Ann Ist Super Sanita 43 139-98
  • [3] Lowe G(2005)Prognostic impact of low-shear whole blood viscosity in hypertensive men Eur J Clin Invest 35 93-51
  • [4] Rumley A(2008)Hemorheological abnormalities in stable angina and acute coronary syndromes Clin Hemorheol Microcirc 39 43-653
  • [5] Fowkes FGR(1986)Blood rheology in myocardial infarction and hypertension Biorheology 23 633-636
  • [6] Allan PL(1988)Blood rheology in patients with transient ischemic attacks Stroke 19 634-1169
  • [7] Caimi G(1991)Hemorheological factors in cerebral ischemia Stroke 22 1164-396
  • [8] Valenti A(2008)Hemorheological disturbances in cerebrovascular diseases Clin Hemorheol Microcirc 39 391-54
  • [9] Lo Presti R(1997)Hemorheologic profiles of plasma fibrinogen and blood viscosity from silent to acute and chronic cerebral infarctions J Neurol Sci 147 49-1748
  • [10] Ciuffetti G(2006)Hyperviscosity as a possible risk factor for cerebral ischemic complications in atrial fibrillation patients Am J Cardiol 97 1745-168