A phase I study evaluating the role of the anti-epidermal growth factor receptor (EGFR) antibody cetuximab as a radiosensitizer with chemoradiation for locally advanced pancreatic cancer

被引：0
作者：
J. P. Arnoletti
A. Frolov
M. Eloubeidi
K. Keene
J. Posey
T. Wood
Edward Greeno
N. Jhala
S. Varadarajulu
S. Russo
J. Christein
R. Oster
D. J. Buchsbaum
S. M. Vickers
机构：
[1] University of Alabama at Birmingham,Department of Surgery
[2] University of Alabama at Birmingham,Department of Gastroenterology
[3] University of Alabama at Birmingham,Department of Radiation Oncology
[4] University of Alabama at Birmingham,Department of Medical Oncology
[5] University of Minnesota,Division of Hematology, Oncology and Transplantation
[6] University of Alabama at Birmingham,Department of Pathology
[7] East Carolina University,Department of Radiation Oncology
[8] University of Alabama at Birmingham,Department of Biostatistics
[9] University of Minnesota, Surgery Department
来源：
Cancer Chemotherapy and Pharmacology | 2011年 / 67卷
关键词：
Cetuximab; Gemcitabine; Radiation therapy; Pancreatic cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：891 / 897
页数：6
相关论文
共 50 条
  • [31] Development of Irinotecan Liposome Armed with Dual-Target Anti-Epidermal Growth Factor Receptor and Anti-Fibroblast Activation Protein-Specific Antibody for Pancreatic Cancer Treatment
    Lin, Hung-Jun
    Liang, Tien-Li
    Chang, Yao-Yuan
    Liu, Der-Zen
    Fan, Jia-Yu
    Roffler, Steve R.
    Lin, Shyr-Yi
    PHARMACEUTICS, 2022, 14 (06)
  • [32] Association between serum ligands and the skin toxicity of anti-epidermal growth factor receptor antibody in metastatic colorectal cancer
    Takahashi, Naoki
    Yamada, Yasuhide
    Furuta, Koh
    Nagashima, Kengo
    Kubo, Akiko
    Sasaki, Yusuke
    Shoji, Hirokazu
    Honma, Yoshitaka
    Iwasa, Satoru
    Okita, Natsuko
    Takashima, Atsuo
    Kato, Ken
    Hamaguchi, Tetsuya
    Shimada, Yasuhiro
    CANCER SCIENCE, 2015, 106 (05) : 604 - 610
  • [33] Anti-Epidermal Growth Factor Receptor (EGFR) Antibodies Overcome Resistance of Ovarian Cancer Cells to Targeted Therapy and Natural Cytotoxicity
    Gottschalk, Nina
    Kimmig, Rainer
    Lang, Stephan
    Singh, Mahavir
    Brandau, Sven
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 13 (09) : 12000 - 12016
  • [34] To Give or Not to Give Anti-Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibodies to Patients With KRAS G13D Mutation in Advanced Colorectal Cancer
    Kim, Richard
    Kubal, Timothy
    CLINICAL COLORECTAL CANCER, 2012, 11 (02) : 85 - 87
  • [35] A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme Clinical article
    Li, Linna
    Quang, Tony S.
    Gracely, Ed J.
    Kim, Ji H.
    Emrich, Jacqueline G.
    Yaeger, Theodore E.
    Jenrette, Joseph M.
    Cohen, Steven C.
    Black, Perry
    Brady, Luther W.
    JOURNAL OF NEUROSURGERY, 2010, 113 (02) : 192 - 198
  • [36] Phase I study of bortezomib and cetuximab in patients with solid tumours expressing epidermal growth factor receptor
    Dudek, A. Z.
    Lesniewski-Kmak, K.
    Shehadeh, N. J.
    Pandey, O. N.
    Franklin, M.
    Kratzke, R. A.
    Greeno, E. W.
    Kumar, P.
    BRITISH JOURNAL OF CANCER, 2009, 100 (09) : 1379 - 1384
  • [37] Phase I study of bortezomib and cetuximab in patients with solid tumours expressing epidermal growth factor receptor
    A Z Dudek
    K Lesniewski-Kmak
    N J Shehadeh
    O N Pandey
    M Franklin
    R A Kratzke
    E W Greeno
    P Kumar
    British Journal of Cancer, 2009, 100 : 1379 - 1384
  • [38] The Role of Anti-Epidermal Growth Factor Receptor and Anti-Vascular Endothelial Growth Factor Therapies in the Treatment of Non-Small-Cell Lung Cancer
    Langer, Corey
    Soria, Jean-Charles
    CLINICAL LUNG CANCER, 2010, 11 (02) : 82 - 90
  • [39] Potential Efficacy of Shiunko for Anti-Epidermal Growth Factor Receptor (EGFR) Monoclonal Antibody-Induced Skin Fissure: A Single Institutional Case Series
    Okunaka, Mashiro
    Kotani, Daisuke
    Mishima, Saori
    Nakamura, Maho
    Kawazoe, Akihito
    Bando, Hideaki
    Yoshino, Takayuki
    Shitara, Kohei
    INTEGRATIVE CANCER THERAPIES, 2024, 23
  • [40] Effect of KRAS Mutational Status in Advanced Colorectal Cancer on the Outcomes of Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: A Systematic Review and Meta-analysis
    Lin, Albert Y.
    Buckley, Nicholas S.
    Lu, An-Ting T.
    Kouzminova, Natalia B.
    Salpeter, Shelley R.
    CLINICAL COLORECTAL CANCER, 2011, 10 (01) : 63 - 69
12345