A view into the catalytic pocket of cyclic nucleotide phosphodiesterases

被引：0
作者：
Marco Conti
机构：
[1] Stanford University School of Medicine,Division of Reproductive Biology of the Department of Obstetrics and Gynecology
来源：
Nature Structural & Molecular Biology | 2004年 / 11卷
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摘要：
Cyclic nucleotide phosphodiesterases are widely expressed enzymes that function as critical components of cell signaling pathways. In a new study, key interactions in the catalytic pocket essential for substrate selectivity have been identified for these enzymes, thus introducing novel perspectives for drug design.
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页码：809 / 810
页数：1
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