Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K/AKT and Telomerase

被引:2
作者
Maliheh Moradzadeh
Azar Hosseini
Saiedeh Erfanian
Hadi Rezaei
机构
[1] Mashhad University of Medical Sciences,Department of New Sciences and Technology, School of Medicine
[2] Mashhad University of Medical Sciences,Pharmacological Research Center of Medicinal Plants, School of Medicine
[3] Jahrom University of Medical Sciences,Research center for non
[4] Jahrom University of Medical Sciences,Communicable Diseases
来源
Pharmacological Reports | 2017年 / 69卷
关键词
Breast cancer; Epigallocatechin-3-gallate; Telomerase; Apoptosis; PI3K/AKT signaling cascade;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:924 / 928
页数:4
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  • [1] Mousavi SM(2009)Cancer incidence and mortality in Iran Ann Oncol 20 556-63
  • [2] Gouya MM(2000)Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate Biochem Biophys Res Commun 275 328-34
  • [3] Ramazani R(2016)Suppressive effects of tea catechins on breast cancer Nutrients 8 458-80
  • [4] Davanlou M(2003)Cancer chemoprevention with dietary phytochemicals Nat Rev Cancer 3 768-47
  • [5] Hajsadeghi N(2013)Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions Biochem Pharmacol 86 1239-502
  • [6] Seddighi Z(2010)Phytochemicals: cancer chemoprevention and suppression of tumor onset and metastasis Cancer Metastasis Rev 29 483-71
  • [7] Ahmad N(2008)Plant-derived compounds in clinical trials Drug Discov Today 13 161-85
  • [8] Cheng P(2003)Molecular pathway for (—)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells Arch Biochem Biophys 410 177-24
  • [9] Mukhtar H(2009)The potential role of green tea catechins in the prevention of the metabolic syndrome-a review Phytochemistry 70 11-99
  • [10] Xiang L-P(2014)Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3K/Akt/FoxO1, and NF-kappa B pathways Eur J Nutr 53 187-406