Unravelling mechanisms of p53-mediated tumour suppression

被引:0
|
作者
Kathryn T. Bieging
Stephano Spano Mello
Laura D. Attardi
机构
[1] Stanford University School of Medicine,Division of Radiation and Cancer Biology, Department of Radiation Oncology
[2] Stanford University School of Medicine,Department of Genetics
来源
Nature Reviews Cancer | 2014年 / 14卷
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摘要
There are many cellular outcomes attributable to p53 activation, but identifying which of these, or which combination of these, is important for tumour suppression has remained challenging. As new roles for p53 emerge, this Opinion dissects the role of p53 in tumour suppression.
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页码:359 / 370
页数:11
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