Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesity

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作者
Daniel Oehler
André Spychala
Axel Gödecke
Alexander Lang
Norbert Gerdes
Jorge Ruas
Malte Kelm
Julia Szendroedi
Ralf Westenfeld
机构
[1] Heinrich-Heine University,Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty
[2] Heinrich-Heine University,Cardiovascular Research Institute Düsseldorf (CARID), Medical Faculty
[3] Heinrich-Heine University Düsseldorf,Department of Cardiovascular Physiology
[4] Karolinska Institutet,Molecular and Cellular Exercise Physiology, Department of Physiology and Pharmacology
[5] Heidelberg University Hospital,Joint Heidelberg
[6] German Center for Diabetes Research,IDC Translational Diabetes Program, Internal Medicine
来源
BMC Biology | / 20卷
关键词
Ischemia/reperfusion; Long-read sequencing; PGC-1α; Diet-induced obesity;
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  • [1] Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesity
    Oehler, Daniel
    Spychala, Andre
    Godecke, Axel
    Lang, Alexander
    Gerdes, Norbert
    Ruas, Jorge
    Kelm, Malte
    Szendroedi, Julia
    Westenfeld, Ralf
    BMC BIOLOGY, 2022, 20 (01) : 169