Role of chromosomal rearrangements and conserved chromosome regions in amniote evolution

被引:0
作者
D. M. Larkin
机构
[1] University of Illinois at Urbana-Champaign,Institute of Cytology and Genetics, Siberian Branch
[2] Russian Academy of Sciences,undefined
来源
Molecular Genetics, Microbiology and Virology | 2010年 / 25卷
关键词
comparative genomics; genome evolution; amniotes;
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暂无
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学科分类号
摘要
Specific features of the evolution of chromosomes in mammals and other amniotes are reviewed. A comparative analysis of the chromosome architecture revealed the nonrandom distribution of chromosome rearrangement sites in the genome, the probable role of chromosome rearrangement in adaptation, and the evolution-mediated selection of conserved chromosome blocks. Chromosome sites stable during evolution are enriched for genes that contribute to early organism development. Rearrangements within these blocks are incompatible with the survival of the organism. Further analysis of chromosome evolution requires more information about completely sequenced genomes.
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页码:1 / 7
页数:6
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