Synthesis, characteristics and biological activity of pentacoordinated spirophosphoranes derived from amino acids

被引：0
|
作者：
L. Yu
Z. Liu
H. Fang
Q. L. Zeng
Y. F. Zhao
机构：
[1] The Key Laboratory for Chemical Biology of Fujian Province,Department of Chemistry
[2] Xiamen University,undefined
来源：
Amino Acids | 2005年 / 28卷
关键词：
Keywords: Pentacoordinated spirophosphoranes – ; P NMR – TBP – Tyrosinase inhibition;
D O I：
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学科分类号：
摘要：
The reactions of phosphorus trichloride with various amino acids afford the pentacoordinated spirophosphoranes. The reaction procedures were traced by 31P NMR spectra techniques. A new crystal structure of alanine derivative was characterized, which is a slightly distorted TBP structure. Besides, this kind of spirophosphoranes are potent inhibitors to tyrosinase.
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页码：369 / 372
页数：3
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