Oral Chemotherapy in the Treatment of Hormone-Refractory Prostate Cancer

被引:0
作者
Kenneth J. Pienta
Jeffrey M. Kamradt
David C. Smith
机构
[1] The University of Michigan School of Medicine,The University of Michigan Comprehensive Cancer Center, Division of Hematology/Oncology, Department of Internal Medicine
来源
Drugs | 1999年 / 58卷
关键词
Prostate Cancer; Paclitaxel; Adis International Limited; Etoposide; Nuclear Matrix;
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中图分类号
学科分类号
摘要
Oral chemotherapy has become a major component of the treatment of advanced prostate cancer. The recognition that prostate cancer grows very slowly and must be treated continuously with active agents has led to the development of several therapeutic regimens. These regimens employ oral agents such as estramustine, cyclophosphamide, and etoposide, as they can be taken on a daily basis at home by the patients. These regimens have demonstrated activity in patients with hormone-refractory prostate cancer; declines in both prostate specific antigen and soft tissue lesions have been demonstrated.
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页码:127 / 131
页数:4
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