Importance of CD4+ Helper T-cells in Antitumor Immunity

被引：0

作者：

Hiroshi Shiku

机构：

[1] Mie University,Second Department of Internal Medicine

[2] School of Medicine,undefined

来源：

International Journal of Hematology | 2003年 / 77卷

关键词：

Tumor antigen; Peptide; CTL; Helper T-cells; MHC;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

CD8+ cytotoxic T-lymphocytes are major effector cells involved in immunologically specific tumor destruction in vivo, and CD4+ T-cells are essential for controlling this CD8+ T-cell-dependent tumor eradication. The presence of CD4+ T-cells with distinct functional roles has been recognized. The further understanding of the complexity of antitumor immune responses by CD4+ T-cells may be crucial for designing more effective cancer vaccines.

引用

页码：435 / 438

页数：3

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