Importance of CD4+ Helper T-cells in Antitumor Immunity

被引：0
作者：
Hiroshi Shiku
机构：
[1] Mie University,Second Department of Internal Medicine
[2] School of Medicine,undefined
来源：
International Journal of Hematology | 2003年 / 77卷
关键词：
Tumor antigen; Peptide; CTL; Helper T-cells; MHC;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
CD8+ cytotoxic T-lymphocytes are major effector cells involved in immunologically specific tumor destruction in vivo, and CD4+ T-cells are essential for controlling this CD8+ T-cell-dependent tumor eradication. The presence of CD4+ T-cells with distinct functional roles has been recognized. The further understanding of the complexity of antitumor immune responses by CD4+ T-cells may be crucial for designing more effective cancer vaccines.
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收藏
页码：435 / 438
页数：3
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