Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy

[1] Savarino A(2006)A historical sketch of the discovery and development of HIV-1 integrase inhibitors Expert Opin Investig Drugs 15 1507-1522

[2] Cotelle P(2006)Patented HIV-1 integrase inhibitors (1998-2005) Recent Pat Antiinfect Drug Discov 1 1-15

[3] Steigbigel RT(2008)Raltegravir with optimized background therapy for resistant HIV-1 infection N Engl J Med 359 339-354

[4] Cooper DA(2002)Patented small molecule inhibitors of HIV-1 integrase: a 10-year saga Expert Opin Ther Patents 12 709-724

[5] Kumar PN(2006)HAART-persistent HIV-1 latent reservoirs: their origin, mechanisms of stability and potential strategies for eradication Curr HIV Res 4 199-208

[6] Eron JE(2007)Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus J Infect Dis 195 1734-1736

[7] Schechter M(2004)Can HIV be cured? Mechanisms of HIV persistence and strategies to combat it Curr HIV Res 2 99-111

[8] Markowitz M(2009)HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation Nat Med 15 893-900

[9] Loutfy MR(2009)"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence Retrovirology 6 52-9

[10] Lennox JL(2009)Novel humanized murine models for HIV research Curr HIV/AIDS Rep 6 13-307

[1] Savarino A(2006)A historical sketch of the discovery and development of HIV-1 integrase inhibitors Expert Opin Investig Drugs 15 1507-1522

[2] Cotelle P(2006)Patented HIV-1 integrase inhibitors (1998-2005) Recent Pat Antiinfect Drug Discov 1 1-15

[3] Steigbigel RT(2008)Raltegravir with optimized background therapy for resistant HIV-1 infection N Engl J Med 359 339-354

[4] Cooper DA(2002)Patented small molecule inhibitors of HIV-1 integrase: a 10-year saga Expert Opin Ther Patents 12 709-724

[5] Kumar PN(2006)HAART-persistent HIV-1 latent reservoirs: their origin, mechanisms of stability and potential strategies for eradication Curr HIV Res 4 199-208

[6] Eron JE(2007)Decay of the HIV reservoir in patients receiving antiretroviral therapy for extended periods: implications for eradication of virus J Infect Dis 195 1734-1736

[7] Schechter M(2004)Can HIV be cured? Mechanisms of HIV persistence and strategies to combat it Curr HIV Res 2 99-111

[8] Markowitz M(2009)HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation Nat Med 15 893-900

[9] Loutfy MR(2009)"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence Retrovirology 6 52-9

[10] Lennox JL(2009)Novel humanized murine models for HIV research Curr HIV/AIDS Rep 6 13-307