Ischaemic preconditioning may abolish the protection afforded by ATP-sensitive potassium channel openers in isolated human atrial muscle

被引：0
作者：
C. S. Carr
D. M. Yellon
机构：
[1] London Hospitals,The Hatter Institute Department of Academic and Clinical Cardiology University College
来源：
Basic Research in Cardiology | 1997年 / 92卷
关键词：
Ischaemic preconditioning; K; channel openers; human atrium; pre-operative nicorandil;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The ATP-sensitive potassium channel (KATP channel) has been implicated in the mechanism underlying ischaemic preconditioning protection. This study based on human atrium compared the protective effects of ischaemic preconditioning with pre-operative nicorandil (a KATP channel opener with nitrate actions). We also examined the added effect of ischaemic preconditioning to that of nicorandil on ischaemic protection. The protective effects of other KATP channel openers devoid of nitrate actions were also examined.
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页码：252 / 260
页数：8
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