An efficient and facile multicomponent synthesis of 4,6-diarylpyridine derivatives under solvent-free conditions

被引：0
|
作者：
Hassan A. El-Sayed
Nabil H. Ouf
Ahmed H. Moustafa
机构：
[1] Zagazig University,Department of Chemistry, Faculty of Science
[2] Tabuk University,Department of Chemistry, Faculty of Science
来源：
Research on Chemical Intermediates | 2014年 / 40卷
关键词：
Multicomponent synthesis; Solvent-free conditions; Pyridine-3-carbonitrile;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We present an efficient and facile synthesis of 4,6-diaryl-2-oxo-1,2-dihydropyridine-3-carbonitriles (5a–j) via a four-component system of aromatic aldehydes (1), acetophenones (2), ethyl cyanoacetate (3), and ammonium acetate (4). The short reaction time coupled with the simplicity of the reaction procedure and clean reaction make this method one of the most efficient methods for synthesis of this class of compounds.
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页码：407 / 412
页数：5
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