METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinoma

被引:0
作者
Yingtong Wu
Ning Chang
Yong Zhang
Xinxin Zhang
Leidi Xu
Yinggang Che
Tianyun Qiao
Bin Wu
Ying Zhou
Jun Jiang
Jie Xiong
Jian Zhang
Jian Zhang
机构
[1] Xijing Hospital,Department of Respiratory Diseases
[2] Fourth Military Medical University,State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology
[3] Fourth Military Medical University,Department of Thoracic Surgery, Tangdu Hospital
[4] Fourth Military Medical University,undefined
来源
Journal of Experimental & Clinical Cancer Research | / 40卷
关键词
METTL3; FBXW7; Lung adenocarcinoma; m; A; Epigenetic modification;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 217 条
  • [1] Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
  • [2] Ferlay J(2019)Tracing Oncogene Rearrangements in the Mutational History of Lung Adenocarcinoma Cell 177 1842-1857
  • [3] Soerjomataram I(2016)Recent advances in SCF ubiquitin ligase complex: clinical implications Biochim Biophys Acta 1866 12-22
  • [4] Siegel R(2014)Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities Cancer Cell 26 455-464
  • [5] Torre L(2019)Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis J Hepatol 71 742-752
  • [6] Jemal A(2009)p53-altered FBXW7 expression determines poor prognosis in gastric cancer cases Cancer Res 69 3788-3794
  • [7] Lee J(2007)The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease Nat Rev Mol Cell Biol 8 904-916
  • [8] Park S(2013)The many faces of C/EBPδ and their relevance for inflammation and cancer Int J Biol Sci 9 917-933
  • [9] Park H(2013)The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia J Exp Med 210 1545-1557
  • [10] Kim S(2017)Epitranscriptomics: regulation of mRNA metabolism through modifications Curr Opin Chem Biol 41 93-98