Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction

[1] Awad SS(2003)State-of-the-art therapy for severe sepsis and multisystem organ dysfunction Am J Surg 186 23-30

[2] Marshall JC(1995)Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome Crit Care Med 23 1638-1652

[3] Cook DJ(2002)Multiple organ dysfunction associated with severe acute pancreatitis Crit Care Med 30 1274-1279

[4] Christou NV(2001)Objective estimates of the incidence and consequences of multiple organ dysfunction and sepsis after burn trauma J Trauma 50 510-515

[5] Bernard GR(2001)Lipopolysaccharide-binding protein (LBP) and markers of acute-phase response in patients with multiple organ dysfunction syndrome (MODS) following open heart surgery Thorac Cardiovasc Surg 49 273-278

[6] Sprung CL(1995)The natural history of the systemic inflammatory response syndrome (SIRS) JAMA 273 117-123

[7] Sibbald WJ(2003)Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome JAMA 289 2104-2112

[8] Halonen KI(1998)From ventilator-induced lung injury to multiple organ dysfunction? Intensive Care Med 24 102-104

[9] Pettila V(1998)Multiple system organ failure. Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med 157 1721-1725

[10] Leppaniemi AK(2004)Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin Am J Physiol Lung Cell Mol Physiol 287 L533-L542

[1] Awad SS(2003)State-of-the-art therapy for severe sepsis and multisystem organ dysfunction Am J Surg 186 23-30

[2] Marshall JC(1995)Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome Crit Care Med 23 1638-1652

[3] Cook DJ(2002)Multiple organ dysfunction associated with severe acute pancreatitis Crit Care Med 30 1274-1279

[4] Christou NV(2001)Objective estimates of the incidence and consequences of multiple organ dysfunction and sepsis after burn trauma J Trauma 50 510-515

[5] Bernard GR(2001)Lipopolysaccharide-binding protein (LBP) and markers of acute-phase response in patients with multiple organ dysfunction syndrome (MODS) following open heart surgery Thorac Cardiovasc Surg 49 273-278

[6] Sprung CL(1995)The natural history of the systemic inflammatory response syndrome (SIRS) JAMA 273 117-123

[7] Sibbald WJ(2003)Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome JAMA 289 2104-2112

[8] Halonen KI(1998)From ventilator-induced lung injury to multiple organ dysfunction? Intensive Care Med 24 102-104

[9] Pettila V(1998)Multiple system organ failure. Is mechanical ventilation a contributing factor? Am J Respir Crit Care Med 157 1721-1725

[10] Leppaniemi AK(2004)Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin Am J Physiol Lung Cell Mol Physiol 287 L533-L542