Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

[1] Prentki M(2006)Islet beta cell failure in type 2 diabetes J Clin Invest 116 1802-1812

[2] Nolan CJ(2013)Metabolic signaling in fuel-induced insulin secretion Cell Metab 18 162-185

[3] Prentki M(2012)Sirtuin biology and relevance to diabetes treatment Diabetes Manag (Lond) 2 243-257

[4] Matschinsky FM(2008)SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin Nature 452 492-496

[5] Madiraju SR(2009)Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6 Cell Cycle 8 2664-2666

[6] Dong XC(2009)The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability Cell Cycle 8 2662-2663

[7] Michishita E(2012)The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis Mol Cell 48 900-913

[8] McCord RA(2010)Human SIRT6 promotes DNA end resection through CtIP deacetylation Science 329 1348-1353

[9] Berber E(2014)Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion Proc Natl Acad Sci U S A 111 10684-10689

[10] Michishita E(2013)SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine Nature 496 110-113

[1] Prentki M(2006)Islet beta cell failure in type 2 diabetes J Clin Invest 116 1802-1812

[2] Nolan CJ(2013)Metabolic signaling in fuel-induced insulin secretion Cell Metab 18 162-185

[3] Prentki M(2012)Sirtuin biology and relevance to diabetes treatment Diabetes Manag (Lond) 2 243-257

[4] Matschinsky FM(2008)SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin Nature 452 492-496

[5] Madiraju SR(2009)Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6 Cell Cycle 8 2664-2666

[6] Dong XC(2009)The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability Cell Cycle 8 2662-2663

[7] Michishita E(2012)The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis Mol Cell 48 900-913

[8] McCord RA(2010)Human SIRT6 promotes DNA end resection through CtIP deacetylation Science 329 1348-1353

[9] Berber E(2014)Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion Proc Natl Acad Sci U S A 111 10684-10689

[10] Michishita E(2013)SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine Nature 496 110-113