Interactions of Quantum Dots with Donor Blood Erythrocytes In Vitro

被引:0
作者
S. N. Pleskova
E. E. Pudovkina
E. R. Mikheeva
E. N. Gorshkova
机构
[1] Nizhny Novgorod State Technological University,Engineering Physicochemical Faculty
来源
Bulletin of Experimental Biology and Medicine | 2014年 / 156卷
关键词
quantum dots; erythrocytes; atomic force microscopy;
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摘要
The effects of quantum dots CdSe/ZnS-mercaptopropionic acid, (CdSe/CdZnS)ZnS-polyT, and CdSeCdSZnS/polyT/SiO2-NH2 on human erythrocytes were studied. The nanomaterials reduced signifi cantly the erythrocyte sedimentation rate and modified the erythrocyte membrane resistance to induced (acid and hypo-osmotic) hemolysis. Evaluation of the erythrocyte morphology by atomic force microscopy in the control and after exposure to quantum dots showed significant differences in erythrocyte size and changes in their morphology as a result of exposure to the nanomaterials.
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页码:384 / 388
页数:4
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