Senescent hepatic stellate cells caused by deoxycholic acid modulates malignant behavior of hepatocellular carcinoma

被引：0
|
作者：
Phuong Thao Nguyen
Keishi Kanno
Quoc Thang Pham
Yuka Kikuchi
Masaki Kakimoto
Tomoki Kobayashi
Yuichiro Otani
Nobusuke Kishikawa
Mutsumi Miyauchi
Koji Arihiro
Masanori Ito
Susumu Tazuma
机构：
[1] Hiroshima University Hospital,Department of General Internal Medicine
[2] Hiroshima University Graduate School of Biomedical and Health Sciences,Department of Molecular Pathology
[3] University of Medicine and Pharmacy at Ho Chi Minh City,Department of Pathology
[4] Hiroshima University Graduate School of Biomedical and Health Sciences,Department of Oral Maxillo
[5] Hiroshima University Hospital,Pathobiology
来源：
Journal of Cancer Research and Clinical Oncology | 2020年 / 146卷
关键词：
Deoxycholic acid; Cellular senescence; Hepatic stellate cells; Hepatocellular carcinoma; Epithelial mesenchymal transition; Senescence-associated secretory phenotype;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：3255 / 3268
页数：13
相关论文
共 50 条
  • [41] ERK pathway activation contributes to the tumor-promoting effects of hepatic stellate cells in hepatocellular carcinoma
    Xie, Yu-Xiao
    Liao, Rui
    Pan, Long
    Du, Cheng-You
    IMMUNOLOGY LETTERS, 2017, 188 : 116 - 123
  • [42] Activated hepatic stellate cells promote progression of post-heat residual hepatocellular carcinoma from autophagic survival to proliferation
    Zhang, Rui
    Lin, Xia-Hui
    Liu, Hua-Hua
    Ma, Min
    Chen, Jie
    Chen, Jun
    Gao, Dong-Mei
    Cui, Jie-Feng
    Chen, Rong-Xin
    INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2019, 36 (01) : 253 - 263
  • [43] Synthesis of pectin-deoxycholic acid conjugate for targeted delivery of anticancer drugs in hepatocellular carcinoma
    Varshosaz, Jaleh
    Sadri, Farzaneh
    Rostami, Mahboubeh
    Mirian, Mina
    Taymouri, Somayeh
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 139 : 665 - 677
  • [44] Rat hepatic stellate cells alter the gene expression profile and promote the growth, migration and invasion of hepatocellular carcinoma cells
    Wang, Zhi-Ming
    Zhou, Le-Yuan
    Liu, Bin-Bin
    Jia, Qin-An
    Dong, Yin-Ying
    Xia, Yun-Hong
    Ye, Sheng-Long
    MOLECULAR MEDICINE REPORTS, 2014, 10 (04) : 1725 - 1733
  • [45] Extracellular vesicles from senescent hepatic stellate cells promote cell viability of hepatoma cells through increasing EGF secretion from differentiated THP-1 cells
    Miyazoe, Yuri
    Miuma, Satoshi
    Miyaaki, Hisamitsu
    Kanda, Yasuko
    Nakashiki, Suguru
    Sasaki, Ryu
    Haraguchi, Masafumi
    Shibata, Hidetaka
    Honda, Takuya
    Taura, Naota
    Nakao, Kazuhiko
    BIOMEDICAL REPORTS, 2020, 12 (04) : 163 - 170
  • [46] Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells – evidence for a role in hepatocellular carcinoma growth in vivo
    Franziska Mußbach
    Hendrik Ungefroren
    Bernd Günther
    Kathrin Katenkamp
    Petra Henklein
    Martin Westermann
    Utz Settmacher
    Lennart Lenk
    Susanne Sebens
    Jörg P. Müller
    Frank-Dietmar Böhmer
    Roland Kaufmann
    Molecular Cancer, 15
  • [47] Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells - evidence for a role in hepatocellular carcinoma growth in vivo
    Mussbach, Franziska
    Ungefroren, Hendrik
    Guenther, Bernd
    Katenkamp, Kathrin
    Henklein, Petra
    Westermann, Martin
    Settmacher, Utz
    Lenk, Lennart
    Sebens, Susanne
    Mueller, Joerg P.
    Boehmer, Frank-Dietmar
    Kaufmann, Roland
    MOLECULAR CANCER, 2016, 15
  • [48] Activated hepatic stellate cells promote hepatocellular carcinoma cell migration and invasion via the activation of FAK-MMP9 signaling
    Han, Shaoshan
    Han, Lei
    Yao, Yingmin
    Sun, Hao
    Zan, Xianfeng
    Liu, Qingguang
    ONCOLOGY REPORTS, 2014, 31 (02) : 641 - 648
  • [49] Clinical significance and gene expression study of human hepatic stellate cells in HBV related-hepatocellular carcinoma
    Liao, Rui
    Wu, Han
    Yi, Yong
    Wang, Jia-Xing
    Cai, Xiao-Yan
    He, Hong-Wei
    Cheng, Yun-Feng
    Zhou, Jian
    Fan, Jia
    Sun, Jian
    Qiu, Shuang-Jian
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2013, 32
  • [50] Clinical significance and gene expression study of human hepatic stellate cells in HBV related-hepatocellular carcinoma
    Rui Liao
    Han Wu
    Yong Yi
    Jia-Xing Wang
    Xiao-Yan Cai
    Hong-Wei He
    Yun-Feng Cheng
    Jian Zhou
    Jia Fan
    Jian Sun
    Shuang-Jian Qiu
    Journal of Experimental & Clinical Cancer Research, 32
12345