Azithromycin ameliorated cigarette smoke-induced airway epithelial barrier dysfunction by activating Nrf2/GCL/GSH signaling pathway

被引：0
|
作者：
Yun Song
Wenhuan Fu
Youzhi Zhang
Doudou Huang
Jian Wu
Shuangmei Tong
Mingkang Zhong
Huifang Cao
Bin Wang
机构：
[1] Huashan Hospital,Department of Pharmacy
[2] Fudan University,Department of Respiration
[3] Huashan Hospital,Institute of Chinese Materia Medica
[4] Fudan University,Department of Respiratory and Critical Medicine
[5] Shanghai University of Traditional Chinese Medicine,undefined
[6] Jing’an District Centre Hospital of Shanghai (Huashan Hospital Fudan University Jing’an Branch),undefined
来源：
Respiratory Research | / 24卷
关键词：
Airway epithelial barrier dysfunction; GSH metabolism; Nrf2; Azithromycin; Cigarette smoke;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] HDAC6-selective inhibitor CAY10603 ameliorates cigarette smoke-induced small airway remodeling by regulating epithelial barrier dysfunction and reversing
    Zhang, Qin
    Yan, Liming
    Lu, Ye
    Liu, Xiaodong
    Yin, Yan
    Wang, Qiuyue
    Gu, Xiu
    Zhou, Xiaoming
    RESPIRATORY RESEARCH, 2024, 25 (01)
  • [42] Activation of the UPR Protects against Cigarette Smoke-induced RPE Apoptosis through Up-Regulation of Nrf2
    Huang, Chuangxin
    Wang, Joshua J.
    Ma, Jacey H.
    Jin, Chenjin
    Yu, Qiang
    Zhang, Sarah X.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (09) : 5367 - 5380
  • [43] Honokiol ameliorates cigarette smoke-induced damage of airway epithelial cells via the SIRT3/SOD2 signalling pathway
    Li, Fei
    Ye, Chunyu
    Wang, Xiuli
    Li, Xinting
    Wang, Xiaoxia
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2023, 27 (24) : 4009 - 4020
  • [44] A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention
    Prange, Ruben
    Thiedmann, Marcus
    Bhandari, Anita
    Mishra, Neha
    Sinha, Anupam
    Haesler, Robert
    Rosenstiel, Philip
    Uliczka, Karin
    Wagner, Christina
    Yildirim, Ali Onder
    Fink, Christine
    Roeder, Thomas
    AGING-US, 2018, 10 (08): : 2122 - 2135
  • [45] Isoliquiritigenin Inhibits Cigarette Smoke-Induced COPD by Attenuating Inflammation and Oxidative Stress via the Regulation of the Nrf2 and NF-κB Signaling Pathways
    Yu, Duo
    Liu, Xueshibojie
    Zhang, Guangxin
    Ming, Zhihui
    Wang, Tiejun
    FRONTIERS IN PHARMACOLOGY, 2018, 9
  • [46] Novel oral edaravone attenuates diastolic dysfunction of diabetic cardiomyopathy by activating the Nrf2 signaling pathway
    Wang, Ling
    Zeng, Yue-Qin
    Gu, Juan-Hua
    Song, Rui
    Cang, Peng-Hui
    Xu, Yong-Xuan
    Shao, Xiao-xia
    Pu, Li-Jin
    Luo, Hai-Yun
    Zhou, Xin-Fu
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2022, 920
  • [47] Andrographolide attenuates inflammatory response induced by LPS via activating Nrf2 signaling pathway in bovine endometrial epithelial cells
    Fu, Kaiqiang
    Chen, Hao
    Wang, Zezhi
    Cao, Rongfeng
    RESEARCH IN VETERINARY SCIENCE, 2021, 134 : 36 - 41
  • [48] Melatonin protects against particulate matter-induced ovarian dysfunction by activating the Nrf2 signaling pathway to alleviate ferroptosis
    Zhang, Xiaoyuan
    Man, Xiaxia
    Zhang, Qi
    Zhu, Laiyu
    Chen, Lu
    Zhu, Chao
    Ci, Xinxin
    Yu, Xiaowei
    LIFE SCIENCES, 2024, 359
  • [49] Breviscapine attenuates lead-induced myocardial injury by activating the Nrf2 signaling pathway
    Li, Dexuan
    Xu, Zhengliang
    Li, Yashan
    Huang, Yanmei
    Yin, Jiali
    Li, Hongjuan
    Zhang, Beiji
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2024, 27 (01)
  • [50] Metformin Protects Alveolar Epithelial Cell Type-2 From Cigarette Smoke-Induced Metabolic Dysfunction
    Rojas-Quintero, J. J.
    Kue, J. T.
    Granato, E.
    Esposito, R.
    Coarfa, C.
    Cloonan, S. M.
    Polverino, F.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
12345