p53: Biology and Role for Cellular Radiosensitivity

被引:0
|
作者
Jochen Dahm-Daphi
机构
[1] Department of Radiotherapy and Oncology,
[2] University of Hamburg,undefined
[3] Germany,undefined
来源
Strahlentherapie und Onkologie | 2000年 / 176卷
关键词
Key Words: Apoptosis; DSB; Exonuclease; G1-arrest; Irradiation; p53; Radiotherapy; Recombination; Tumor; X-rays; Schlüsselwörter: Apoptose; Doppelstrangbruch; G1-Arrrest; p53; Rekombination; Röntgenstrahlen; Strahlentherapie; Tumor;
D O I
暂无
中图分类号
学科分类号
摘要
p53 is the most commonly mutated gene in human tumors with large impact on cellular biology and response to radiation. Many excellent reviews are available on various aspects but for several years none about the role of p53 for radiosensitivity. The latter is the aim of the present paper.
引用
收藏
页码:278 / 285
页数:7
相关论文
共 50 条
  • [1] p53: Biology and role for cellular radiosensitivity
    Dahm-Daphi, J
    STRAHLENTHERAPIE UND ONKOLOGIE, 2000, 176 (06) : 278 - 285
  • [2] The role of p53 in chemosensitivity and radiosensitivity
    Wafik S El-Deiry
    Oncogene, 2003, 22 : 7486 - 7495
  • [3] The role of p53 in chemosensitivity and radiosensitivity
    El-Deiry, WS
    ONCOGENE, 2003, 22 (47) : 7486 - 7495
  • [4] p53 status and radiosensitivity
    Bodis, S
    Pruschy, M
    Glanzmann, C
    Krek, W
    Lowe, SW
    Fisher, DE
    PROGRESS IN RADIO-ONCOLOGY VI, 1998, : 481 - 489
  • [5] Role of p53 mutations in the radiosensitivity status of tumor cells
    Chiarugi, V
    Magnelli, L
    Cinelli, M
    TUMORI, 1998, 84 (05) : 517 - 520
  • [6] Role of p53 in the Regulation of Cellular Senescence
    Mijit, Mahmut
    Caracciolo, Valentina
    Melillo, Antonio
    Amicarelli, Fernanda
    Giordano, Antonio
    BIOMOLECULES, 2020, 10 (03)
  • [7] On the role of p53 in the cellular response to aneuploidy
    Narkar, Akshay
    Johnson, Blake A.
    Bharne, Pandurang
    Zhu, Jin
    Padmanaban, Veena
    Biswas, Debojyoti
    Fraser, Andrew
    Iglesias, Pablo A.
    Ewald, Andrew J.
    Li, Rong
    CELL REPORTS, 2021, 34 (12):
  • [8] p53: Radiosensitivity and antiangiogenic effects
    Chiarugi, V
    Cinelli, M
    Magnelli, L
    MOLECULAR GENETICS AND METABOLISM, 1998, 64 (01) : 7 - 11
  • [9] The role of DNA damage responses in p53 biology
    Speidel, Daniel
    ARCHIVES OF TOXICOLOGY, 2015, 89 (04) : 501 - 517
  • [10] Role of p53 in the biology of oligodendroglioma - An immunohistochemical analysis
    Pal, L
    Behari, S
    Datta, N
    Gupta, R
    BRAIN PATHOLOGY, 2000, 10 (04) : 570 - 570