Functional activity of hepatocytes in tissue fragments in a new bioreactor biological artificial liver

被引：0
作者：
V. V. Solov'ev
V. S. Akatov
E. I. Lezhnev
机构：
[1] Russian Academy of Sciences,Laboratory of Cytotechnology, Institute of Theoretical and Experimental Biophysics
来源：
Bulletin of Experimental Biology and Medicine | 2000年 / 129卷
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摘要：
Functional activity of hepatocytes in a new bioreactor designed for culturing of liver tissue fragments under perfusion conditions was tested. Specific hepatic functions such as ammonium detoxification, urea and protein synthesis, and P-450-dependent metabolism of p-nitroanisole were maintained for 1–1.5 days. The bioreactor can be used as a bioartificial liver support apparatus.
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页码：595 / 597
页数：2
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