Features of laser desorption/ionization mass spectrometry fragmentation of vitamin B12

被引：0
作者：
Shmygol' I.V. [1 ]
Snegir S.V. [1 ]
Pokrovskii V.A. [1 ]
机构：
[1] A. A. Chuiko Institute of Surface Chemistry, National Academy of Sciences of Ukraine, Kyiv 03164, Vul. Generala Naumova
来源：
Theoretical and Experimental Chemistry | 2007年 / 43卷 / 4期
关键词：
2,5-dihydroxybenzoic acid; DIOS mass spectrometry; MALDI mass spectrometry; Porous silicon; Vitamin B[!sub]12[!/sub;
D O I：
10.1007/s11237-007-0033-z
中图分类号：
学科分类号：
摘要：
A comparative analysis of the laser desorption/ionization of vitamin B 12 by matrix-assisted laser desorption/ionization (MALDI) and desorption/ionization on porous silicon (DIOS) was carried out. The mass spectra obtained were interpreted and the pathways for ion formation and decomposition were established. The MALDI fragmentation of the positive vitamin B12 ions is more extensive than the DIOS fragmentation. The most extensive fragmentation was found using the MALDI method for negative vitamin B 12 ions, which are lacking when using the DIOS method. © 2007 Springer Science+Business Media, Inc.
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页码：272 / 277
页数：5
相关论文
共 13 条
  • [1] Hillenkamp F., Karas M., Beavis R., Chait B., Anal. Chem., 63, (1991)
  • [2] Lebedev A.T., Mass Spectrometry in Organic Chemistry, (2003)
  • [3] Gluckmann M., Pfenninger A., Kruger R., Et al., Int. J. Mass Spectrom., 210, pp. 121-132, (2001)
  • [4] Wei J., Buriak J., Siuzdak G., Nature, 399, pp. 243-246, (1999)
  • [5] Kinsel R., Preston M., Russell H., Biological Mass Spectrom., 23, pp. 205-211, (1994)
  • [6] MacFarlane R., Torgerson D., Science, 191, pp. 920-925, (1976)
  • [7] Ens W., Standing K., Anal. Chem., 53, pp. 1241-1244, (1981)
  • [8] Shulten H., Scheielbel H., Naturwissenschaften, 65, pp. 223-230, (1978)
  • [9] Chen Y., Ling Y., J. Mass Spectrom., 37, pp. 716-730, (2002)
  • [10] Hill H.A.O., Eichhorn G., Inorganic Biochemistry, pp. 523-598, (1978)
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