Pattern visual evoked potentials in the assessment of objective visual acuity in amblyopic children

被引：12
作者：
Gundogan F.C. [1 ]
Mutlu F.M. [1 ]
Altinsoy H.I. [1 ]
Tas A. [1 ]
Oz O. [2 ]
Sobaci G. [1 ]
机构：
[1] Department of Ophthalmology, Gulhane Military Medical Academy, 06010 Etlik, Ankara, Göz Hastaliklari A.D
[2] Department of Neurology, Gulhane Military Medical Academy, Ankara
来源：
International Ophthalmology | 2010年 / 30卷 / 4期
关键词：
Amblyopia; Check size; Pattern visual evoked potentials; Visual acuity;
D O I：
10.1007/s10792-010-9361-4
中图分类号：
学科分类号：
摘要：
The aim of this study was to determine the value of pattern visual evoked potentials (PVEP) to five consecutive check size patterns in the assessment of visual acuity (VA) in children. One hundred unilateral amblyopic (study group) and 90 healthy children with best-corrected visual acuity (BCVA) of 1.0 (control group) were planned to be included. PVEP responses to five consecutive check sizes (2°, 1°, 30′, 15′, and 7′) which are assumed to correspond to VAs of 0.1, 0.2, 0.4, 0.7 and 1.0 Snellen lines were recorded in both groups. Eighty-five children in the study group (85.0%) and 74 children in the control group (82.2%) who cooperated well with PVEP testing were included. Normal values for latency, amplitude, and normalized interocular amplitude/ latency difference in each check size were defined in the control group. PVEP-estimated VA (PVEPVA) in the amblyopic eye was defined by the normal PVEP responses to the smallest check size associated with normal interocular difference from the nonamblyopic eye, and was considered predictive if it is within ±1 Snellen line (1 decimal) discrepancy with BCVA in that eye. Mean age was 9.7 ± 1.9 and 9.9 ± 2.2 years in the study and the control groups, respectively. LogMAR (logarithm of minimum angle of resolution) Snellen acuity was well correlated with the logMAR PVEP-VA (r = 0.525, P<0.001) in the study group. The Snellen line discrepancy between BCVA and PVEP-VA was within ±1 Snellen line in 57.6% of the eyes. PVEP to five consecutive check sizes may predict objective VA in amblyopic children. © Springer Science+Business Media B.V. 2010.
引用
收藏
页码：377 / 383
页数：6
相关论文
共 22 条
  • [1] Von Noorden G.K., Binocular Vision and Ocular Motility: Theory and Management of Strabismus, (2002)
  • [2] Kirschen D.G., Flom M.C., Visual acuity at different retinal loci of eccentrically fixating functional amblyopia, Am J Optom Physiol Opt, 55, pp. 144-150, (1978)
  • [3] Jenkins T.C., Douthwaite W.A., An objective VER assessment of visual acuity compared with subjective measures, Am J Optom Physiol Opt, 65, pp. 957-961, (1988)
  • [4] Muller W., Schoneich H., Relations between visual acuity, refraction and the pattern reversal visual-evoked cortical potential in aphakia, Ophthalmologica, 198, pp. 89-94, (1989)
  • [5] Ohn Y.H., Katsumi O., Matsui Y., Tetsuka H., Hirose T., Snellen visual acuity versus pattern reversal visualevoked response acuity in clinical applications, Ophthalmic Res, 26, pp. 240-252, (1994)
  • [6] Simon F., Rassow B., Retinal visual acuity with pattern VEP normal subjects and reproducibility, Graefes Arch Clin Exp Ophthalmol, 224, pp. 160-164, (1986)
  • [7] Sokol S., Hansen V.C., Moskowitz A., Greenfield P., Towle V.L., Evoked potential and preferential looking estimates of visual acuity in pediatric patients, Ophthalmology, 90, pp. 552-562, (1983)
  • [8] Chan H., Odom J.V., Coldren J., Dove C., Chao G.M., Acuity estimated by visually evoked potentials is affected by scaling, Doc Ophthalmol, 62, pp. 107-117, (1986)
  • [9] Tyler C.W., Apkarian P., Levi D.M., Nakayama K., Rapid assessment of visual function: An electronic sweep technique for the pattern visual evoked potential, Invest Ophthalmol Vis Sci, 18, pp. 703-713, (1979)
  • [10] Gundogan F.C., Sobaci G., Bayer A., Pattern visual evoked potentials in the assessment of visual acuity in malingering, Ophthalmology, 114, pp. 2332-2337, (2007)
123