Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei

被引：0
作者：
Binny M. Mony
Paula MacGregor
Alasdair Ivens
Federico Rojas
Andrew Cowton
Julie Young
David Horn
Keith Matthews
机构：
[1] Centre for Immunity,
[2] Infection and Evolution,undefined
[3] Institute for Immunology and Infection Research,undefined
[4] School of Biological Sciences,undefined
[5] University of Edinburgh,undefined
[6] Edinburgh EH9 3JT,undefined
[7] UK,undefined
[8] Biological Chemistry & Drug Discovery,undefined
[9] College of Life Sciences,undefined
[10] University of Dundee,undefined
[11] Dow Street,undefined
[12] Dundee DD1 5EH,undefined
[13] UK,undefined
来源：
Nature | 2014年 / 505卷
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摘要：
Here a genome-wide RNAi library screen is used to identify components of the signalling pathway that allow transformation of Trypanosoma brucei spp., the protozoan parasite responsible for important human and livestock diseases in sub-Saharan Africa, from proliferative slender forms to arrested stumpy forms which are transmitted to the tsetse fly vector.
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页码：681 / 685
页数：4
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