Adding a transcription-coupled repair pathway

被引：3

作者：

Saponaro, Marco ^{[1
]}

机构：

[1] Univ Birmingham, Inst Canc & Genom Sci, Birmingham, England

来源：

NATURE CELL BIOLOGY | 2024年 / 26卷 / 05期

关键词：

HEMATOPOIETIC STEM-CELLS; HAEMOGENIC ENDOTHELIUM; HEMOGENIC ENDOTHELIUM; VASCULAR ENDOTHELIUM; AORTIC ENDOTHELIUM; IN-VIVO; PROGENITORS; NOTCH; EMERGE; FATE;

D O I：

10.1038/s41556-024-01399-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

When transcription by RNA polymerase II is stalled by ultraviolet-induced DNA damage, it recruits repair factors, leading to excision of the damaged site and DNA synthesis to fill the gap. Three new studies show that, for aldehyde-induced DNA crosslinks, repair is activated by the same factors, but without base excision and gap filling.

引用

页码：670 / 671

页数：2

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