Analysis of the Angiotensinogen Gene T174M Polymorphism in Populations of the Volga–Ural Region

被引：0
作者：
T. R. Nasibullin
O. E. Mustafina
I. A. Tuktarova
V. V. Danilova
E. K. Khusnutdinova
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来源：
Russian Journal of Genetics | 2004年 / 40卷
关键词：
Polymerase Chain Reaction; Ethnic Group; Frequency Distribution; Gene Polymorphism; Genotype Frequency;
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摘要：
The method of polymerase chain reaction was used to analyze T174M polymorphism at the angiotensinogen (AGT) gene in a number of populations of the Volga–Ural region, belonging to Finno–Ugric (Komi-Permyaks, Maris, Mordovians, and Udmurts), Turkic (Chuvashes, Tatars, and Bashkirs), and Eastern-Slavic (Russians) ethnic groups. Population-specific patterns of the polymorphic alleles and genotypes frequency distribution were established. Comparison of the results with the literature data on the AGT gene polymorphism in different world populations provided identification of specific trends in the changes of genotype frequency of the AGT gene depending on the ethnicity of the populations.
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页码：1163 / 1168
页数：5
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