Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027

被引:0
作者
Lifei Wang
Yunfeng Hu
Yanjuan Zhang
Songmei Wang
Zhihui Cui
Yi Bao
Wei Jiang
Bin Hong
机构
[1] Peking Union Medical College,Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences &
来源
BMC Microbiology | / 9卷
关键词
Wild Type Strain; cagA; Biosynthetic Gene Cluster; Native Promoter; Putative Regulatory Gene;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 158 条
[1]  
Hu JL(1988)A new macromolecular antitumor antibiotic, C-1027. I. Discovery, taxonomy of producing organism, fermentation and biological activity J Antibiot (Tokyo) 41 1575-1579
[2]  
Xue YC(1989)A new macromolecular antitumor antibiotic, C-1027. III. Antitumor activity J Antibiot (Tokyo) 42 1294-1298
[3]  
Xie MY(1990)Sequence-specific double-strand breakage of DNA by neocarzinostatin involves different chemical mechanisms within a staggered cleavage site J Biol Chem 265 14713-14716
[4]  
Zhang R(1996)The enediyne antibiotics J Med Chem 39 2103-2117
[5]  
Otani T(2001)Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia Clin Cancer Res 7 1490-1496
[6]  
Minami Y(2008)Enediyne anticancer antibiotic lidamycin: chemistry, biology and pharmacology Anticancer Agents Med Chem 8 123-131
[7]  
Yamada Y(2005)Regulation of secondary metabolism in streptomycetes Curr Opin Microbiol 8 208-215
[8]  
Marunaka T(1991)The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the Cell 66 769-780
[9]  
Zhen YS(1999) tRNA gene of J Bacteriol 181 6958-6968
[10]  
Ming XY(1995)Characterization of the pathway-specific positive transcriptional regulator for actinorhodin biosynthesis in Mol Microbiol 18 151-162