Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis

被引:0
|
作者
M N Khan
T Bhattacharyya
P Andrikopoulos
M A Esteban
R Barod
T Connor
M Ashcroft
P H Maxwell
S Kiriakidis
机构
[1] Centre for Cell Signalling and Molecular Genetics,
[2] Rayne Institute,undefined
[3] University College London,undefined
[4] Stem Cell and Cancer Biology Group,undefined
[5] Key Laboratory of Regenerative Biology,undefined
[6] South China Institute for Stem Cell Biology and Regenerative Medicine,undefined
[7] Guangzhou Institutes of Biomedicine and Health,undefined
[8] Chinese Academy of Sciences,undefined
[9] Current address: Kennedy Institute of Rheumatology Division,undefined
[10] Imperial College London,undefined
[11] 65 Aspenlea Road,undefined
[12] Hammersmith,undefined
[13] W6 8LH,undefined
[14] UK.,undefined
来源
British Journal of Cancer | 2011年 / 104卷
关键词
clear cell; HIF-1; FIH-1; HIF-2; apoptosis; renal carcinoma;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1151 / 1159
页数:8
相关论文
共 50 条
  • [1] Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis
    Khan, M. N.
    Bhattacharyya, T.
    Andrikopoulos, P.
    Esteban, M. A.
    Barod, R.
    Connor, T.
    Ashcroft, M.
    Maxwell, P. H.
    Kiriakidis, S.
    BRITISH JOURNAL OF CANCER, 2011, 104 (07) : 1151 - 1159
  • [2] The Role of Factor Inhibiting HIF (FIH-1) in Inhibiting HIF-1 Transcriptional Activity in Glioblastoma Multiforme
    Wang, Enfeng
    Zhang, Chunyang
    Polavaram, Navatha
    Liu, Fengming
    Wu, Gang
    Schroeder, Mark A.
    Lau, Julie S.
    Mukhopadhyay, Debabrata
    Jiang, Shi-Wen
    O'Neill, Brian Patrick
    Datta, Kaustubh
    Li, Jinping
    PLOS ONE, 2014, 9 (01):
  • [3] Factor-inhibiting HIF-1 (FIH-1) is required for human vascular endothelial cell survival
    Kiriakidis, Serafim
    Henze, Anne-Theres
    Kruszynska-Ziaja, Ilona
    Skobridis, Konstantinos
    Theodorou, Vassiliki
    Paleolog, Ewa M.
    Mazzone, Massimiliano
    FASEB JOURNAL, 2015, 29 (07): : 2814 - 2827
  • [4] Differences in hydroxylation and binding of Notch and HIF-1α demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1)
    Wilkins, Sarah E.
    Hyvarinen, Jaana
    Chicher, Johana
    Gorman, Jeffrey J.
    Peet, Daniel J.
    Bilton, Rebecca L.
    Koivunen, Peppi
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2009, 41 (07): : 1563 - 1571
  • [5] MicroRNA-31 contributes to colorectal cancer development by targeting factor inhibiting HIF-1α (FIH-1)
    Chen, Tao
    Yao, Li-Qing
    Shi, Qiang
    Ren, Zhong
    Ye, Le-Chi
    Xu, Jian-Min
    Zhou, Ping-Hong
    Zhong, Yun-Shi
    CANCER BIOLOGY & THERAPY, 2014, 15 (05) : 516 - 523
  • [6] Regulation of Transactivation at C-TAD Domain of HIF-1α by Factor-Inhibiting HIF-1α (FIH-1): A Potential Target for Therapeutic Intervention in Cancer
    Rani, Soniya
    Roy, Subhadeep
    Singh, Manjari
    Kaithwas, Gaurav
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2022, 2022
  • [7] Factor inhibiting HIF1α (FIH-1) functions as a tumor suppressor in human colorectal cancer by repressing HIF1α pathway
    Chen, Tao
    Ren, Zhong
    Ye, Le-Chi
    Zhou, Ping-Hong
    Xu, Jian-Min
    Shi, Qiang
    Yao, Li-Qing
    Zhong, Yun-Shi
    CANCER BIOLOGY & THERAPY, 2015, 16 (02) : 244 - 252
  • [8] FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
    Mahon, PC
    Hirota, K
    Semenza, GL
    GENES & DEVELOPMENT, 2001, 15 (20) : 2675 - 2686
  • [9] Factor-inhibiting HIF (FIH) promotes lung cancer
    Garcia-del Rio, Ana
    Prieto-Fernandez, Endika
    Egia-Mendikute, Leire
    Antonana-Vildosola, Asier
    Jimenez-Lasheras, Borja
    Lee, So Young
    Barreira-Manrique, Adrian
    Zanetti, Samanta Romina
    de Blas, Ander
    Velasco-Beltran, Paloma
    Bosch, Alexandre
    Aransay, Ana M.
    Palazon, Asis
    JCI INSIGHT, 2023, 8 (20)
  • [10] Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression
    Hyseni, Agon
    van der Groep, Petra
    van der Wall, Elsken
    van Diest, Paul J.
    CELLULAR ONCOLOGY, 2011, 34 (06) : 565 - 570