Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[18F]Fluoro-d-Glucose Uptake in Prostate Cancer Mouse Xenografts

[1] Zadra G(2013)The fat side of prostate cancer Biochim Biophys Acta 1831 1518-1532

[2] Photopoulos C(2003)Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains Biochem Biophys Res Commun 302 898-903

[3] Loda M(2006)Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer Prostate Cancer Prostatic Dis 9 230-234

[4] Swinnen JV(2013)Imaging evaluation of prostate cancer with (18)F-fluorodeoxyglucose PET/CT: utility and limitations Eur J Nucl Med Mol Imaging 1 S5-10

[5] van Veldhoven PP(2008)Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading Cancer Res 68 8607-8615

[6] Timmermans L(2013)Metabolic imaging of patients with prostate cancer using hyperpolarized [1-(13)C]pyruvate Sci Transl Med 5 198ra108-64

[7] De SE(2009)Molecular imaging of prostate cancer: a concise synopsis Mol Imaging 8 56-984

[8] Liu Y(2006)Effect of hypoxia on the uptake of [methyl-3H]choline, [1-14C] acetate and [18 F]FDG in cultured prostate cancer cells Nucl Med Biol 33 977-498

[9] Jadvar H(2006)Modification of myocardial substrate use as a therapy for heart failure Nat Clin Pract Cardiovasc Med 3 490-43

[10] Albers MJ(2012)Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle J Mol Med (Berl) 90 31-2371

[1] Zadra G(2013)The fat side of prostate cancer Biochim Biophys Acta 1831 1518-1532

[2] Photopoulos C(2003)Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains Biochem Biophys Res Commun 302 898-903

[3] Loda M(2006)Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer Prostate Cancer Prostatic Dis 9 230-234

[4] Swinnen JV(2013)Imaging evaluation of prostate cancer with (18)F-fluorodeoxyglucose PET/CT: utility and limitations Eur J Nucl Med Mol Imaging 1 S5-10

[5] van Veldhoven PP(2008)Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading Cancer Res 68 8607-8615

[6] Timmermans L(2013)Metabolic imaging of patients with prostate cancer using hyperpolarized [1-(13)C]pyruvate Sci Transl Med 5 198ra108-64

[7] De SE(2009)Molecular imaging of prostate cancer: a concise synopsis Mol Imaging 8 56-984

[8] Liu Y(2006)Effect of hypoxia on the uptake of [methyl-3H]choline, [1-14C] acetate and [18 F]FDG in cultured prostate cancer cells Nucl Med Biol 33 977-498

[9] Jadvar H(2006)Modification of myocardial substrate use as a therapy for heart failure Nat Clin Pract Cardiovasc Med 3 490-43

[10] Albers MJ(2012)Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle J Mol Med (Berl) 90 31-2371