Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement

被引：0
作者：
Di Huang
Shanshan Li
Menglei Xia
Jianping Wen
Xiaoqiang Jia
机构：
[1] Tianjin University,Department of Biochemical Engineering, School of Chemical Engineering and Technology
[2] Ministry of Education,TEDA School of Biological Sciences and Biotechnology
[3] Key Laboratory of Systems Bioengineering,undefined
[4] Nankai University,undefined
[5] TEDA,undefined
来源：
Microbial Cell Factories | / 12卷
关键词：
FK506; Genome-scale metabolic model; Target prediction; Metabolic engineering; Combinatorial modification;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Genome-scale metabolic model in guiding metabolic engineering of microbial improvement
    Xu, Chuan
    Liu, Lili
    Zhang, Zhao
    Jin, Danfeng
    Qiu, Juanping
    Chen, Ming
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2013, 97 (02) : 519 - 539
  • [22] Combination of atmospheric and room temperature plasma (ARTP) mutagenesis, genome shuffling and dimethyl sulfoxide (DMSO) feeding to improve FK506 production in Streptomyces tsukubaensis
    Ye, Liting
    Ye, Ruifang
    Hu, Fengxian
    Wang, Guozhu
    BIOTECHNOLOGY LETTERS, 2021, 43 (09) : 1809 - 1820
  • [23] Improved FK506 production by the precursors and product-tolerant mutant of Streptomyces tsukubaensis based on genome shuffling and dynamic fed-batch strategies
    Du, Wenjie
    Huang, Di
    Xia, Menglei
    Wen, Jianping
    Huang, Ming
    JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2014, 41 (07) : 1131 - 1143
  • [24] Improvement of FK506 production by synthetic biology approaches
    Fu, Li-Feng
    Tao, Yang
    Jin, Mei-Ying
    Jiang, Hui
    BIOTECHNOLOGY LETTERS, 2016, 38 (12) : 2015 - 2021
  • [25] Improvement of FK506 production by synthetic biology approaches
    Li-Feng Fu
    Yang Tao
    Mei-Ying Jin
    Hui Jiang
    Biotechnology Letters, 2016, 38 : 2015 - 2021
  • [26] Application of a combined approach involving classical random mutagenesis and metabolic engineering to enhance FK506 production in Streptomyces sp RM7011
    Mo, SangJoon
    Lee, Sung-Kwon
    Jin, Ying-Yu
    Oh, Chung-Hun
    Suh, Joo-Won
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2013, 97 (07) : 3053 - 3062
  • [27] Genome-scale metabolic network reconstruction of Saccharopolyspora spinosa for Spinosad Production improvement
    Xiaoyang Wang
    Chuanbo Zhang
    Meiling Wang
    Wenyu Lu
    Microbial Cell Factories, 13
  • [28] Genome-scale metabolic network reconstruction of Saccharopolyspora spinosa for Spinosad Production improvement
    Wang, Xiaoyang
    Zhang, Chuanbo
    Wang, Meiling
    Lu, Wenyu
    MICROBIAL CELL FACTORIES, 2014, 13
  • [29] Optimization of FK-506 production in Streptomyces tsukubaensis by modulation of Crp-mediated regulation
    Schulz, Susann
    Sletta, Havard
    Flogstad Degnes, Kristin
    Krysenko, Sergii
    Williams, Alicia
    Olsen, Silje Malene
    Vernstad, Kai
    Mitulski, Agnieszka
    Wohlleben, Wolfgang
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2023, 107 (09) : 2871 - 2886
  • [30] Application of a combined approach involving classical random mutagenesis and metabolic engineering to enhance FK506 production in Streptomyces sp. RM7011
    SangJoon Mo
    Sung-Kwon Lee
    Ying-Yu Jin
    Chung-Hun Oh
    Joo-Won Suh
    Applied Microbiology and Biotechnology, 2013, 97 : 3053 - 3062
12345