Cytoreductive nephrectomy for metastatic RCC in the era of targeted therapy

被引：0
作者：
E. Jason Abel
Christopher G. Wood
机构：
[1] University of Texas M. D. Anderson Cancer Center,Department of Urology
来源：
Nature Reviews Urology | 2009年 / 6卷
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摘要：
The development of targeted therapy for renal cell carcinoma (RCC) has changed the treatment options for patients with metastatic RCC. The authors of this Review discuss the current and future role of cytoreductive nephrectomy in combination with targeted therapies, and the rationale for presurgical therapy for this group of patients.
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页码：375 / 383
页数：8
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[11]  
Evans CP(2007)Sorafenib in advanced clear-cell renal-cell carcinoma N. Engl. J. Med. 356 125-134
[12]  
Lara PN(2008)Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial Lancet 372 449-456
[13]  
Flanigan RC(2007)Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma N. Engl. J. Med. 356 2271-2281
[14]  
Mickisch GH(2008)Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206 J. Clin. Oncol. 26 5422-5428
[15]  
Latif F(2007)Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study Lancet Oncol. 8 975-984
[16]  
Foster K(2008)Pazopanib, a potent orally administered small-molecule multitargeted tyrosine kinase inhibitor for renal cell carcinoma Expert Opin. Investig. Drugs 17 253-261
[17]  
Kim WY(1967)Surgery for metastatic renal cell carcinoma J. Urol. 97 973-977
[18]  
Kaelin WG(1982)Spontaneous regression of metastatic renal cell carcinoma Urology 20 177-181
[19]  
Motzer RJ(1995)Cytoreductive surgery for stage IV renal cell carcinoma J. Urol. 154 32-34
[20]  
Escudier B(2004)Cytoreductive nephrectomy in patients with metastatic renal cancer: a combined analysis J. Urol. 171 1071-1076
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