Liver involvement in Langerhans cell histiocytosis

被引:0
作者
Adelaine Wong
Clara L. Ortiz-Neira
Walid Abou Reslan
Raphael Sharon
Alfredo Pinto-Rojas
Deepak Kaura
Ronald Anderson
机构
[1] Alberta Children’s Hospital,Department of Diagnostic Imaging
[2] Alberta Children’s Hospital,Department of Oncology
[3] Alberta Children’s Hospital,Department of Pathology
来源
Pediatric Radiology | 2006年 / 36卷
关键词
Langerhans cell histiocytosis; Liver involvement; Children; Ultrasound; CT; MRI·MRCP;
D O I
暂无
中图分类号
学科分类号
摘要
Liver involvement in Langerhans cell histiocytosis (LCH) typically presents with hepatomegaly and other signs of liver dysfunction. We present an 11-month-old child having only minimally elevated liver enzymes as an indication of liver involvement. Using sonography as the initial diagnostic tool followed by MRI, LCH of the liver was revealed. A review of sonographic, CT, MRI and MR cholangiopancreatography findings in liver LCH is presented. We recommend that physicians consider sonography and MRI screening for liver involvement in patients with newly diagnosed LCH, as periportal involvement may be present with little or no liver function abnormality present, as in this patient.
引用
收藏
页码:1105 / 1107
页数:2
相关论文
共 18 条
  • [1] Henter JI(2004)Histiocyte disorders Crit Rev Oncol Hematol 50 157-174
  • [2] Tondini C(1995)Langerhans cell histiocytosis J Pediatr 127 1-11
  • [3] Pritchard J(1996)A multicentre retrospective survey of Langerhans’ cell histiocytosis: 348 cases observed between 1983 and 1993 Arch Dis Child 75 17-24
  • [4] Egeler RM(2004)Liver involvement in the histiocytic disorders of childhood Pediatr Dev 7 214-225
  • [5] D’Angio GJ(2003)Paediatric manifestations of Langerhans cell histiocytosis: a review of the clinical and radiological findings Clin Radiol 58 269-278
  • [6] Jaffe R(2004)Extra-osseous involvement of Langerhans’ cell histiocytosis in children Pediatr Radiol 34 313-321
  • [7] Kilborn TN(2001)MR cholangiography in the diagnosis of sclerosing cholangitis in Langerhans’ cell histiocytosis Eur Radiol 11 2516-2520
  • [8] Teh J(1999)Langerhans’ cell histiocytosis as a cause of periportal abnormal signal intensity on MRI Abdom Imaging 24 373-377
  • [9] Goodman TR(undefined)undefined undefined undefined undefined-undefined
  • [10] Schmidt S(undefined)undefined undefined undefined undefined-undefined