FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib

被引：0
|
作者：
Lixia Gao
Xuli Wang
Yaoliang Tang
Shuang Huang
Chien-An Andy Hu
Yong Teng
机构：
[1] Augusta University,Department of Oral Biology, Dental College of Georgia
[2] University of Utah,Department of Radiology and Imaging Sciences, School of Medicine
[3] University of Utah,Experimental Therapeutics Program, Huntsman Cancer Institute
[4] Augusta University,Vascular Biology Center, Department of Medicine, Medical College of Georgia
[5] University of Florida College of Medicine,Department of Anatomy and Cell Biology
[6] University of New Mexico School of Medicine,Department of Biochemistry and Molecular Biology
[7] Augusta University,Department of Biochemistry and Molecular Biology, Medical College of Georgia
来源：
Journal of Experimental & Clinical Cancer Research | / 36卷
关键词：
FGF19; FGFR4; Hepatocellular carcinoma; Drug resistance; Sorafenib; Synergistic effect;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib
    Gao, Lixia
    Wang, Xuli
    Tang, Yaoliang
    Huang, Shuang
    Hu, Chien-An Andy
    Teng, Yong
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 36
  • [2] Expression of FGF19/FGFR4 related biomarkers in hepatocellular carcinoma
    Lin, Zhong-Zhe
    Jeng, Yung -Ming
    Hsu, Chiun
    Tsai, I-Lun
    Chen, Kuan-Yu
    Hu, Fu -Chang
    Hsu, Chih-Hung
    Hsu, Hey-Chi
    Cheng, Ann-Lii
    CANCER RESEARCH, 2016, 76
  • [3] Combined inhibition of FGFR4 and VEGFR signaling enhances efficacy in FGF19 driven hepatocellular carcinoma
    Zhao, Xuesong
    Joshi, Jaya Julie
    Aird, Daniel
    Karr, Craig
    Yu, Kun
    Huang, Chialing
    Colombo, Federico
    Virrankoski, Milena
    Prajapati, Sudeep
    Selvaraj, Anand
    AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 12 (06): : 2733 - +
  • [4] The impact of FGF19/FGFR4 signaling inhibition in antitumor activity of multi-kinase inhibitors in hepatocellular carcinoma
    Kanzaki, Hiroaki
    Chiba, Tetsuhiro
    Ao, Junjie
    Koroki, Keisuke
    Kanayama, Kengo
    Maruta, Susumu
    Maeda, Takahiro
    Kusakabe, Yuko
    Kobayashi, Kazufumi
    Kanogawa, Naoya
    Kiyono, Soichiro
    Nakamura, Masato
    Kondo, Takayuki
    Saito, Tomoko
    Nakagawa, Ryo
    Ogasawara, Sadahisa
    Suzuki, Eiichiro
    Ooka, Yoshihiko
    Muroyama, Ryosuke
    Nakamoto, Shingo
    Yasui, Shin
    Tawada, Akinobu
    Arai, Makoto
    Kanda, Tatsuo
    Maruyama, Hitoshi
    Mimura, Naoya
    Kato, Jun
    Zen, Yoh
    Ohtsuka, Masayuki
    Iwama, Atsushi
    Kato, Naoya
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [5] The impact of FGF19/FGFR4 signaling inhibition in antitumor activity of multi-kinase inhibitors in hepatocellular carcinoma
    Hiroaki Kanzaki
    Tetsuhiro Chiba
    Junjie Ao
    Keisuke Koroki
    Kengo Kanayama
    Susumu Maruta
    Takahiro Maeda
    Yuko Kusakabe
    Kazufumi Kobayashi
    Naoya Kanogawa
    Soichiro Kiyono
    Masato Nakamura
    Takayuki Kondo
    Tomoko Saito
    Ryo Nakagawa
    Sadahisa Ogasawara
    Eiichiro Suzuki
    Yoshihiko Ooka
    Ryosuke Muroyama
    Shingo Nakamoto
    Shin Yasui
    Akinobu Tawada
    Makoto Arai
    Tatsuo Kanda
    Hitoshi Maruyama
    Naoya Mimura
    Jun Kato
    Yoh Zen
    Masayuki Ohtsuka
    Atsushi Iwama
    Naoya Kato
    Scientific Reports, 11
  • [6] FGF19 amplification reveals an oncogenic dependency upon autocrine FGF19/FGFR4 signaling in head and neck squamous cell carcinoma
    Lixia Gao
    Liwei Lang
    Xiangdong Zhao
    Chloe Shay
    Austin Y. Shull
    Yong Teng
    Oncogene, 2019, 38 : 2394 - 2404
  • [7] FGF19 amplification reveals an oncogenic dependency upon autocrine FGF19/FGFR4 signaling in head and neck squamous cell carcinoma
    Gao, Lixia
    Lang, Liwei
    Zhao, Xiangdong
    Shay, Chloe
    Shull, Austin Y.
    Teng, Yong
    ONCOGENE, 2019, 38 (13) : 2394 - 2404
  • [8] FGFR4 provides the conduit to facilitate FGF19 signaling in breast cancer progression
    Zhao, Xiangdong
    Xu, Faliang
    Dominguez, Nestor P.
    Xiong, Yuanping
    Xiong, Zhongxun
    Peng, Hong
    Shay, Chloe
    Teng, Yong
    MOLECULAR CARCINOGENESIS, 2018, 57 (11) : 1616 - 1625
  • [9] Hepatocellular Carcinoma: IGF/FGF Signaling Pathway contributes to Sorafenib Resistance
    Weiss, Johannes
    ZEITSCHRIFT FUR GASTROENTEROLOGIE, 2017, 55 (07):
  • [10] FGF19-FGFR4 Signaling in Hepatocellular Carcinoma
    Raja, Aroosha
    Park, Inkeun
    Haq, Farhan
    Ahn, Sung-Min
    CELLS, 2019, 8 (06)
12345