Pyridine-based, microwave-assisted one-pot synthetic protocol for the synthesis of ethyl 3-substituted-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates

被引：0

作者：

Sourabh Mundra

Radhakrishnan Mahesh

机构：

[1] Birla Institute of Technology and Science,Department of Pharmacy, FD

[2] Pilani,III

来源：

Research on Chemical Intermediates | 2016年 / 42卷

关键词：

5-Carboethoxy-2-thiouracil; Thiourea; Pyrimidine; Microwave irradiation; Synthesis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Pyridine has been used for one-pot, two-component synthesis of ethyl 3-substituted-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives in moderate to good yields by condensing N-substituted thioureas with diethyl ethoxymalonate under microwave irradiation.

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页码：4207 / 4219

页数：12

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