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Loessner D(2006)A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b Nat Cell Biol 8 894-896
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Biniossek ML(2006)SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production Nat Cell Biol 8 843-848
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Kizhakkedathu JN(2007)The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells Cell Death Differ 14 1678-1687
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Clements JA(2014)The intramembrane proteases Signal-peptide-peptidase-like 2a and b (SPPL2a/b) have distinct functions in vivo Mol Cell Biol 34 1398-1411
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Magdolen V(2013)The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain J Exp Med 210 23-30
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Schilling O(2013)B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A J Exp Med 210 31-40
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Voss M(2013)The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain J Exp Med 210 41-58