Muscling in on the ryanodine receptor

被引:0
|
作者
Ivana Y Kuo
Barbara E Ehrlich
机构
[1] Yale University School of Medicine,Ivana Y. Kuo and Barbara E. Ehrlich are at the Department of Pharmacology and the Department of Cellular and Molecular Physiology
[2] New Haven,undefined
[3] Connecticut,undefined
[4] USA.,undefined
来源
Nature Structural & Molecular Biology | 2015年 / 22卷
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摘要
The ryanodine receptor (RyR), an ion channel regulating intracellular calcium release in excitable cells, has been challenging for structural analysis because of its colossal proportions compared to most other ion channels. Three independent groups have now used recent technological advancements in single-particle cryo-EM to make giant strides in solving the structure of this elusive protein complex.
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页码:106 / 107
页数:1
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