The current role and future prospectives of functional parameters by diffusion weighted imaging in the assessment of histologic grade of HCC

被引：0

作者：

Vincenza Granata

Roberta Fusco

Salvatore Filice

Orlando Catalano

Mauro Piccirillo

Raffaele Palaia

Francesco Izzo

Antonella Petrillo

机构：

[1] Istituto Nazionale Tumori IRCCS Fondazione G. Pascale – IRCCS di Napoli,Radiology Division

[2] Istituto Nazionale Tumori IRCCS Fondazione G. Pascale – IRCCS di Napoli,Hepatobiliary Surgical Oncology Division

来源：

Infectious Agents and Cancer | / 13卷

关键词：

HCC; Magnetic resonance imaging; Diffusion weighted imaging; Histologic grade;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Hepatocellular carcinoma (HCC) is one of the most common human solid malignancies worldwide. Although the MRI is the technique that is best adapted to characterize HCC, there is not an agreement regarding the study protocol and even what the role of Diffusion-weighted imaging (DWI). The possibility that imaging study can correlate to histologic grade to selecting the therapeutic strategy would be valuable in helping to direct the proper management of HCC. Apparent Diffusion Coefficient (ADC) and IVIM-derived perfusion fraction (fp) and tissue diffusivity (Dt) values of HCC showed significantly better diagnostic performance in differentiating high-grade HCC from low-grade HCC, and significant correlation was observed between ADC, fp, Dt and histological grade.

引用