Irreversible Electroporation in Locally Advanced Pancreatic Adenocarcinoma: Aiming to Improve Overall Survival

被引：0
|
作者：
Diego Tristán Enjuto
Norberto Herrera Merino
José María Abadal Villandrade
Esther Gálvez González
Rosa Llorente Lázaro
Patricia Díaz Peña
María Jesús Álvarez Pérez
Marta Pérez González
机构：
[1] Hospital Universitario Severo Ochoa,General and Digestive Surgery Department
[2] Hospital Universitario Severo Ochoa,Interventional Radiology Department
来源：
Journal of Gastrointestinal Cancer | 2020年 / 51卷
关键词：
Locally advanced pancreatic cancer; Ablation techniques; Irreversible electroporation;
D O I：
暂无
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学科分类号：
摘要：
Irreversible electroporation (IRE) is a non-thermic ablation therapy which has been proposed for locally advanced pancreatic adenocarcinoma (LAPC) as well as for the local control of other types of tumors (kidney or liver). Its use has been extended in the last few years worldwide. Its advantage over other ablation techniques is that it only affects the lipids bilayer of the cell membrane avoiding vascular damage. Safety and viability have been demonstrated in recent studies. Overall survival seems (OS) to improve when it is combined with chemotherapy compared to chemotherapy with or without radiotherapy. Clinical trials should confirm these encouraging data.
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页码：1084 / 1087
页数：3
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