Synthesis and anti-acetylcholinesterase activity of benzotriazinone-triazole systems

被引:0
作者
SETAREH MOGHIMI
FERESHTEH GOLI-GARMROODI
HEDIEH PILALI
MOHAMMAD MAHDAVI
LOGHMAN FIROOZPOUR
HAMID NADRI
ALIREZA MORADI
ALI ASADIPOUR
ABBAS SHAFIEE
ALIREZA FOROUMADI
机构
[1] Tehran University of Medical Sciences,Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center
[2] Tehran University of Medical Sciences,Drug Design and Development Research Center
[3] Shahid Sadoughi University of Medical Sciences,Department of Medicinal Chemistry, Faculty of Pharmacy
[4] Kerman University of Medical Sciences,Department of Medicinal Chemistry, Faculty of Pharmacy and Neuroscience Research Center, Institute of Neuropharmacology
来源
Journal of Chemical Sciences | 2016年 / 128卷
关键词
triazole; benzotriazinone; diazonium chemistry; nanocatalyst; acetylcholinesterase;
D O I
暂无
中图分类号
学科分类号
摘要
An approach for the construction of benzotriazinone-triazole system is described. The synthesis is based on diazonium chemistry and subsequent intramolecular heteroatom-heteroatom bond formation. The introduction of triazole moiety occurred via click reaction catalyzed by nano-sized copper, supported on modified silica mesopore KIT-5 leading to the desired products in excellent yield. Also, in vitro acetylcholinesterase (AChE) inhibitory activities of the target compounds were screened by Ellman’s method.
引用
收藏
页码:1445 / 1449
页数:4
相关论文
共 50 条
[41]   Synthesis by microwave irradiation and antidiarrhoeal activity of benzotriazinone and saccharine derivatives [J].
Fiorino, F ;
Caliendo, G ;
Perissutti, E ;
Severino, B ;
Frecentese, F ;
Preziosi, B ;
Izzo, AA ;
Capasso, R ;
Santagada, V .
ARCHIV DER PHARMAZIE, 2005, 338 (11) :548-555
[42]   Anti-inflammatory, Anti-bacterial and Anti-acetylcholinesterase Activities of two Isoquinoline Alkaloids Scoulerine and Cheilanthifoline [J].
Wangchuk, Phurpa ;
Sastraruji, Thanapat ;
Taweechotipatr, Malai ;
Keller, Paul A. ;
Pyne, Stephen G. .
NATURAL PRODUCT COMMUNICATIONS, 2016, 11 (12) :1801-1804
[43]   Phenolic Derivatives with Anti-Acetylcholinesterase Inhibitory Activities from Galeola nudifolia in Vietnam [J].
Do, Kiep Minh ;
Nakashima, Yu ;
Kodama, Takeshi ;
Lee, Yuan-E ;
Nguyen, Hien Minh ;
Ikumi, Naotaka ;
Morita, Hiroyuki .
CHEMISTRY & BIODIVERSITY, 2023, 20 (12)
[44]   Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer's disease [J].
Wei, Shenqi ;
Chen, Wei ;
Qin, Jingfang ;
Huangli, Yingzi ;
Wang, Li ;
Shen, Yue ;
Tang, Huang .
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 24 (22) :6031-6039
[45]   Antioxidant, Anti-Skin-Aging, Anti-Inflammatory, and Anti-Acetylcholinesterase Activities of Rourea oligophlebia Extracts [J].
Buranasudja, Visarut ;
Vimolmangkang, Sornkanok ;
Sanookpan, Kittipong ;
Binalee, Asma ;
Nguyen, Anh Bao ;
Thach, Ut Dong ;
Do, Bich Hang ;
Dang, Van Son ;
Do, Kiep Minh ;
Nguyen, Hien Minh .
CHEMISTRY & BIODIVERSITY, 2023, 20 (04)
[46]   Study of the Composition and Anti-Acetylcholinesterase Activity of Olive Leaf (Olea europea L.) Extracts Obtained in Subcritical Water [J].
Khizrieva, S. S. ;
Borisenko, S. N. ;
Maksimenko, E., V ;
Borisenko, N., I ;
Minkin, V., I .
RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B, 2021, 15 (08) :1286-1290
[47]   Green synthesis of Kickxia elatine-induced silver nanoparticles and their role as anti-acetylcholinesterase in the treatment of Alzheimer's disease [J].
Huda, Noor Ul ;
Ghneim, Hazem K. ;
Fozia, Fozia ;
Ahmed, Mushtaq ;
Mushtaq, Nadia ;
Sher, Naila ;
Khan, Rahmat Ali ;
Ahmad, Ijaz ;
Al-Sheikh, Yazeed A. ;
Giesy, John P. ;
Aboul-Soud, Mourad A. M. .
GREEN PROCESSING AND SYNTHESIS, 2023, 12 (01)
[48]   Antioxidant, Anti-acetylcholinesterase and Composition of Biochemical Components of Russian Deer Velvet Antler Extracts [J].
Je, Jae-Young ;
Park, Pyo-Jam ;
Lim, Dong Hwan ;
Jeon, Byong-Tae ;
Kho, Kang Hee ;
Ahn, Chang-Bum .
KOREAN JOURNAL FOR FOOD SCIENCE OF ANIMAL RESOURCES, 2011, 31 (03) :349-355
[49]   Two New Picoline-Derived Meroterpenoids with Anti-Acetylcholinesterase Activity from Ascidian-Derived Fungus Amphichorda felina [J].
Jiang, Minghua ;
Guo, Heng ;
Wu, Qilin ;
Yuan, Siwen ;
Liu, Lan .
MOLECULES, 2022, 27 (16)
[50]   Active anti-acetylcholinesterase component of secondary metabolites produced by the endophytic fungi of Huperzia serrata [J].
Wang, Zhejian ;
Ma, Zhao ;
Wang, Lili ;
Tang, Chengchen ;
Hu, Zhibi ;
Chou, GuiXin ;
Li, Wankui .
ELECTRONIC JOURNAL OF BIOTECHNOLOGY, 2015, 18 (06) :399-405