A New Sesquiterpenoid-Geranylbenzene Conjugate from the Roots of Lindera chunii

被引:0
作者
Songsong Wen
Qiyang Li
Qi Liu
Yanli Dou
Chong Niu
Yuwen Xu
Na Zhang
Weijian Wang
机构
[1] Shandong University,Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine
[2] Shandong Research Center of Engineering and Technology for Consistency Evaluation of Generic Drugs,NMPA Key Laboratory for Research and Evaluation of Generic Drugs
[3] Shandong Institute for Food and Drug Control,undefined
来源
Chemistry of Natural Compounds | 2022年 / 58卷
关键词
sesquiterpenoid; lindechunisin A; cytotoxic activity;
D O I
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中图分类号
学科分类号
摘要
Lindechunisin A, a new sesquiterpenoid-geranylbenzene conjugate, was isolated from the roots of Lindera chunii. The structure of this compound was characterized by extensive spectroscopic methods. The cytotoxicity evaluation revealed that lindechunisin A showed moderate cytotoxic activity against the HeLa cell line with IC50 value of 52.60 ± 4.22 μM.
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页码:1045 / 1047
页数:2
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