Laboratory Animal Science: A Resource to Improve the Quality of Science

被引：0
作者：
M. Forni
机构：
[1] Università di Bologna,Dipartimento di Morfofisiologia Veterinaria e produzioni Animali
来源：
Veterinary Research Communications | 2007年 / 31卷
关键词：
animal experimentation; quality of science; reduction; refinement; replacement;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The contribution of animal experimentation to biomedical research is of undoubted value, nevertheless the real usefulness of animal models is still being hotly debated. Laboratory Animal Science is a multidisciplinary approach to humane animal experimentation that allows the choice of the correct animal model and the collection of unbiased data. Refinement, Reduction and Replacement, the “3Rs rule”, are now widely accepted and have a major influence on animal experimentation procedures. Refinement, namely any decrease in the incidence or severity of inhumane procedures applied to animals, has been today extended to the entire lives of the experimental animals. Reduction of the number of animals used to obtain statistically significant data may be achieved by improving experimental design and statistical analysis of data. Replacement refers to the development of validated alternative methods.
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页码：43 / 47
页数：4
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