Three-component condensation of 4-aminoisothiazole derivatives with aldehydes and Meldrum’s acid. Synthesis of 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones

被引:0
作者
B. V. Lichitsky
A. N. Komogortsev
R. M. Belyi
A. A. Dudinov
M. M. Krayushkin
机构
[1] Russian Academy of Sciences,N. D. Zelinsky Institute of Organic Chemistry
来源
Russian Chemical Bulletin | 2009年 / 58卷
关键词
4-aminoisothiazoles; three-component condensation; Meldrum’s acid; decar-boxylation; 6,7-dihydro-4; -isothiazolo[4,5-; ]pyridin-5-ones.;
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摘要
A convenient method was developed for the synthesis of previously unknown substituted 6,7-dihydro-4H-isothiazolo[4,5-b]pyridin-5-ones based on the three-component condensation of 4-aminoisothiazole hydrochlorides, Meldrum’s acid, and aromatic aldehydes.
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页码:1538 / 1541
页数:3
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